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    sbcD ATP-dependent structure-specific DNA nuclease - SbcD subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945049, updated on 3-Dec-2024

    Summary

    Official Symbol
    sbcD
    Official Full Name
    ATP-dependent structure-specific DNA nuclease - SbcD subunit
    Primary source
    ECOCYC:EG11094
    Locus tag
    b0398
    See related
    ASAP:ABE-0001383
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0392; yajA
    Summary
    SbcCD can cleave dsDNA 5' ends sealed by a hairpin or by covalent linkage to a protein. [More information is available at EcoGene: EG11094]. sbcD encodes a component of the SbcCD exonuclease . [More information is available at EcoCyc: EG11094].
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    Genomic context

    Sequence:
    NC_000913.3 (415750..416952, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene fructokinase Neighboring gene putative transport protein AraJ Neighboring gene ATP-dependent structure-specific DNA nuclease - SbcC subunit Neighboring gene DNA-binding transcriptional dual regulator PhoB Neighboring gene sensor histidine kinase PhoR

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3'-5' exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA exonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables double-stranded DNA endonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables single-stranded DNA endodeoxyribonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA recombination NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within DNA repair IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in DNA repair NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within DNA replication IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA replication termination EXP
    Inferred from Experiment
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of DNA repair complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    ATP-dependent structure-specific DNA nuclease - SbcD subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      415750..416952 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414932.1 ATP-dependent structure-specific DNA nuclease - SbcD subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414932.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4TPP2, A0A8S7JU23
      Conserved Domains (1) summary
      PRK10966
      Location:1400
      PRK10966; exonuclease subunit SbcD; Provisional