U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    bioH pimeloyl-acyl carrier protein methyl ester esterase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947916, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    bioH
    Official Full Name
    pimeloyl-acyl carrier protein methyl ester esterase
    Primary source
    ECOCYC:EG10122
    Locus tag
    b3412
    See related
    ASAP:ABE-0011136
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    bioB; ECK3399
    Summary
    S. marcescens bioH complements Escherichia coli bioH. [More information is available at EcoGene: EG10122]. BioH exhibits carboxylesterase activity, particularly toward substrates with short acyl chains . [More information is available at EcoCyc: EG10122].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (3544074..3544844, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene Fe(2(+)) transporter FeoB Neighboring gene ferrous iron transport protein FeoC Neighboring gene recombination-promoting nuclease RpnA Neighboring gene DNA utilization protein YhgH Neighboring gene iron-sulfur cluster carrier protein NfuA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Gene cloning, expression, and characterization of a new carboxylesterase from Serratia sp. SES-01: comparison with Escherichia coli BioHe enzyme. Kwon MA, et al. J Microbiol Biotechnol, 2009 Feb. PMID 19307763
    2. Improving simvastatin bioconversion in Escherichia coli by deletion of bioH. Xie X, et al. Metab Eng, 2007 Jul. PMID 17625941
    3. The Serratia marcescens bioH gene encodes an esterase. Akatsuka H, et al. Gene, 2003 Jan 2. PMID 12527210
    4. Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Agarwal V, et al. Proc Natl Acad Sci U S A, 2012 Oct 23. PMID 23045647, Free PMC Article
    5. Origin of carbon atoms of biotin. 13C-NMR studies on biotin biosynthesis in Escherichia coli. Ifuku O, et al. Eur J Biochem, 1994 Mar 1. PMID 8125118

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carboxylesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carboxylic ester hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carboxylic ester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pimelyl-[acyl-carrier protein] methyl ester esterase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pimelyl-[acyl-carrier protein] methyl ester esterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pimelyl-[acyl-carrier protein] methyl ester esterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biotin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biotin biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in biotin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within biotin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    pimeloyl-acyl carrier protein methyl ester esterase
    NP_417871.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3544074..3544844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417871.1 pimeloyl-acyl carrier protein methyl ester esterase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417871.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7TCT8
      Conserved Domains (1) summary
      PRK10349
      Location:1 → 256
      PRK10349; pimeloyl-ACP methyl ester esterase BioH
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.