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    gatA galactitol-specific PTS enzyme IIA component [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946633, updated on 17-Dec-2024

    Summary

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    Official Symbol
    gatA
    Official Full Name
    galactitol-specific PTS enzyme IIA component
    Primary source
    ECOCYC:EG12414
    Locus tag
    b2094
    See related
    ASAP:ABE-0006932
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2087
    Summary
    [More information is available at EcoCyc: EG12414].
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    Genomic context

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    Sequence:
    NC_000913.3 (2174597..2175049, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene galactitol-specific PTS enzyme IIB component Neighboring gene putative tagatose-1,6-bisphosphate aldolase 2 chaperone Neighboring gene tagatose-1,6-bisphosphate aldolase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mutant inducible for galactitol utilization in Escherichia coli K12. Delidakis CE, et al. J Gen Microbiol, 1982 Mar. PMID 7042910
    2. NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA. Volpon L, et al. Protein Sci, 2006 Oct. PMID 16963640, Free PMC Article
    3. Xylitol and D-arabitol toxicities due to derepressed fructose, galactitol, and sorbitol phosphotransferases of Escherichia coli. Reiner AM. J Bacteriol, 1977 Oct. PMID 334721, Free PMC Article
    4. Genotypic exclusion: a novel relationship between the ribitol-arabitol and galactitol genes of E. coli. Link CD, et al. Mol Gen Genet, 1983. PMID 6343795
    5. Mapping of mglB, the structural gene of the galactose-binding protein of Escherichia coli. Boos W, et al. Mol Gen Genet, 1981. PMID 6278261

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NMR spectroscopy solution of the three-dimensional structure of the IIB subunit (GatB). An NMR titration was performed to identify the GatA-interacting residues.
      Title: NMR structure of the enzyme GatB of the galactitol-specific phosphoenolpyruvate-dependent phosphotransferase system and its interaction with GatA.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-phosphocysteine-galactitol-phosphotransferase system transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in galactitol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within galactitol transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in galactitol transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of transmembrane transporter complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    galactitol-specific PTS enzyme IIA component
    NP_416597.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2174597..2175049 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416597.1 galactitol-specific PTS enzyme IIA component [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416597.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X3KA23
      Conserved Domains (1) summary
      PRK09665
      Location:1 → 150
      PRK09665; PTS galactitol transporter subunit IIA
    Nucleotide Protein
    Heading Accession and Version

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