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    metI L-methionine/D-methionine ABC transporter membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944894, updated on 3-Dec-2024

    Summary

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    Official Symbol
    metI
    Official Full Name
    L-methionine/D-methionine ABC transporter membrane subunit
    Primary source
    ECOCYC:EG11737
    Locus tag
    b0198
    See related
    ASAP:ABE-0000668
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0198; metD; yaeE
    Summary
    [More information is available at EcoCyc: EG11737].
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    Genomic context

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    Sequence:
    NC_000913.3 (220968..221621, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA m(6)t(6)A37 methyltransferase Neighboring gene sensor lipoprotein RcsF Neighboring gene L-methionine/D-methionine ABC transporter membrane anchored binding protein Neighboring gene L-methionine/D-methionine ABC transporter ATP binding subunit Neighboring gene D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase Neighboring gene 16S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Kadaba NS, et al. Science, 2008 Jul 11. PMID 18621668, Free PMC Article
    2. Transport and utilization of D-methionine and other methionine sources in Escherichia coli. Kadner RJ. J Bacteriol, 1977 Jan. PMID 318639, Free PMC Article
    3. A distinct mechanism for the ABC transporter BtuCD-BtuF revealed by the dynamics of complex formation. Lewinson O, et al. Nat Struct Mol Biol, 2010 Mar. PMID 20173761, Free PMC Article
    4. Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli. Nobre LS, et al. Microbiology (Reading), 2009 Mar. PMID 19246752
    5. Transcriptional responses of Escherichia coli to S-nitrosoglutathione under defined chemostat conditions reveal major changes in methionine biosynthesis. Flatley J, et al. J Biol Chem, 2005 Mar 18. PMID 15647275

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ABC-type D-methionine transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables L-methionine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in D-methionine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-methionine transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methionine import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within methionine transport EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of methionine-importing ABC transporter complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    L-methionine/D-methionine ABC transporter membrane subunit
    NP_414740.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      220968..221621 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414740.1 L-methionine/D-methionine ABC transporter membrane subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414740.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7SCN9
      Conserved Domains (1) summary
      PRK10782
      Location:1 → 217
      PRK10782; D-methionine ABC transporter permease MetI
    Nucleotide Protein
    Heading Accession and Version

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