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    CG32568 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32659, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32568provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052568
    Locus tag
    Dmel_CG32568
    See related
    AllianceGenome:FB:FBgn0052568
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4724; Dmel\CG32568
    Summary
    Predicted to enable protein phosphatase activator activity. Predicted to be involved in protein dephosphorylation. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32568 in Genome Data Viewer
    Location:
    15A3-15A3; 1-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16740906..16742918)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16634939..16636951)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene gone early Neighboring gene TweedleY Neighboring gene TweedleZ Neighboring gene Tweedlealpha Neighboring gene inflated Neighboring gene mitochondrial ribosomal protein L22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Impaired Wnt signaling in dopamine containing neurons is associated with pathogenesis in a rotenone triggered Drosophila Parkinson's disease model. Stephano F, et al. Sci Rep, 2018 Feb 5. PMID 29403026, Free PMC Article
    2. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
    3. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    4. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in meiotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein phosphatase type 2A complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32568-PB
    CG32568-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16740906..16742918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298422.1 → NP_001285351.1  uncharacterized protein Dmel_CG32568, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285351.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6G2, Q9VXB7
      Conserved Domains (1) summary
      pfam01603
      Location:33 → 297
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    2. NM_167542.3 → NP_728019.3  uncharacterized protein Dmel_CG32568, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728019.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6G2, Q9VXB7
      Conserved Domains (1) summary
      pfam01603
      Location:33 → 297
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXB7 Q9VXB7

    Gene LinkOut

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