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    nmd no mitochondrial derivative [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44021, updated on 9-Dec-2024

    Summary

    Official Symbol
    nmdprovided by FlyBase
    Official Full Name
    no mitochondrial derivativeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0005322
    Locus tag
    Dmel_CG5395
    See related
    AllianceGenome:FB:FBgn0005322
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-1.79; CG5395; clone 1.79; DmCG5395; Dmel\CG5395; l(2)08774; ms(2)4; ms(2)ry4; Msp; Msp1; Nmd
    Summary
    Predicted to enable membrane protein dislocase activity. Involved in wing disc dorsal/ventral pattern formation. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See nmd in Genome Data Viewer
    Location:
    31D1-31D1; 2-41 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10302173..10303947, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10302173..10303947, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cylindromatosis Neighboring gene antisense RNA:CR44968 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding  
    enables ATP hydrolysis activity  
    enables membrane protein dislocase activity  
    Component Evidence Code Pubs
    is_active_in mitochondrial outer membrane  
    located_in mitochondrial outer membrane  

    General protein information

    Preferred Names
    no mitochondrial derivative
    Names
    CG5395-PA
    CG5395-PB
    CG5395-PC
    mitochondrial sorting protein 1
    nmd-PA
    nmd-PB
    nmd-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10302173..10303947 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298872.1 → NP_001285801.1  no mitochondrial derivative, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285801.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL02
      Conserved Domains (2) summary
      smart00382
      Location:132 → 266
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:135 → 265
      AAA; ATPase family associated with various cellular activities (AAA)
    2. NM_001298871.1 → NP_001285800.1  no mitochondrial derivative, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J7P4
      Conserved Domains (2) summary
      smart00382
      Location:52 → 186
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:55 → 185
      AAA; ATPase family associated with various cellular activities (AAA)
    3. NM_135529.3 → NP_609373.1  no mitochondrial derivative, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609373.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL02
      Related
      FBpp0079654
      Conserved Domains (2) summary
      smart00382
      Location:132 → 266
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:135 → 265
      AAA; ATPase family associated with various cellular activities (AAA)
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