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    CG16868 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37298, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG16868provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034498
    Locus tag
    Dmel_CG16868
    See related
    AllianceGenome:FB:FBgn0034498
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG16868
    Summary
    Predicted to enable voltage-gated calcium channel activity. Predicted to be part of voltage-gated calcium channel complex. Is expressed in organism. Orthologous to human CACHD1 (cache domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG16868 in Genome Data Viewer
    Location:
    56F16-56F16; 2-90 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20281629..20287094, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16169134..16174599, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Mitochondrial phosphate carrier protein 1 Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 56F Neighboring gene Casein kinase II beta2 subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Straightjacket/α2δ3 deregulation is associated with cardiac conduction defects in myotonic dystrophy type 1. Auxerre-Plantié E, et al. Elife, 2019 Dec 12. PMID 31829940, Free PMC Article
    2. Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster. Parker GA, et al. G3 (Bethesda), 2020 Mar 5. PMID 31969430, Free PMC Article
    3. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article
    4. Discovery of genes with highly restricted expression patterns in the Drosophila wing disc using DNA oligonucleotide microarrays. Butler MJ, et al. Development, 2003 Feb. PMID 12505997
    5. Cache - a signaling domain common to animal Ca(2+)-channel subunits and a class of prokaryotic chemotaxis receptors. Anantharaman V, et al. Trends Biochem Sci, 2000 Nov. PMID 11084361

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables voltage-gated calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of voltage-gated calcium channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16868-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20281629..20287094 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137625.2 → NP_611469.1  uncharacterized protein Dmel_CG16868 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611469.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5BI42
      Related
      FBpp0085614
      Conserved Domains (2) summary
      pfam02743
      Location:559 → 627
      Cache_1; Cache domain
      cl00057
      Location:308 → 426
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BI42.1 Q5BI42

    Gene LinkOut

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