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    Tango10 Transport and Golgi organization 10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32125, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Tango10provided by FlyBase
    Official Full Name
    Transport and Golgi organization 10provided by FlyBase
    Primary source
    FLYBASE:FBgn0030330
    Locus tag
    Dmel_CG1841
    See related
    AllianceGenome:FB:FBgn0030330
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1841; Dmel\CG1841; tango10; TANGO10
    Summary
    Involved in protein secretion. Located in cytosol. Is expressed in spermatozoon. Orthologous to human BTBD17 (BTB domain containing 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tango10 in Genome Data Viewer
    Location:
    10D7-10D8; 1-35 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11720245..11723854)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11614278..11617887)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45618 Neighboring gene pretaporter Neighboring gene uncharacterized protein Neighboring gene inaF-D Neighboring gene inaF-B Neighboring gene inaF-C Neighboring gene inaF-A Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The E3 ubiquitin ligase adaptor Tango10 links the core circadian clock to neuropeptide and behavioral rhythms. Lee J, et al. Proc Natl Acad Sci U S A, 2021 Nov 23. PMID 34799448, Free PMC Article
    2. Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome. Kong HE, et al. Proc Natl Acad Sci U S A, 2022 May 31. PMID 35617426, Free PMC Article
    3. Spatial specificity of mesodermal even-skipped expression relies on multiple repressor sites. Liu J, et al. Dev Biol, 2008 Jan 15. PMID 18067885, Free PMC Article
    4. Death of a Protein: The Role of E3 Ubiquitin Ligases in Circadian Rhythms of Mice and Flies. Abdalla OHMH, et al. Int J Mol Sci, 2022 Sep 12. PMID 36142478, Free PMC Article
    5. Systematic image-driven analysis of the spatial Drosophila embryonic expression landscape. Frise E, et al. Mol Syst Biol, 2010. PMID 20087342, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The E3 ubiquitin ligase adaptor Tango10 links the core circadian clock to neuropeptide and behavioral rhythms.
      Title: The E3 ubiquitin ligase adaptor Tango10 links the core circadian clock to neuropeptide and behavioral rhythms.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein secretion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transport and golgi organization 10
    Names
    CG1841-PA
    CG1841-PB
    CG1841-PC
    Tango10-PA
    Tango10-PB
    Tango10-PC
    transport and golgi organization

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11720245..11723854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167302.3 → NP_727555.1  transport and golgi organization 10, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727555.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K187
      Related
      FBpp0073397
      Conserved Domains (3) summary
      smart00225
      Location:144 → 242
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:258 → 359
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:135 → 239
      BTB; BTB/POZ domain

    2. NM_001272532.2 → NP_001259461.1  transport and golgi organization 10, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259461.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K187
      Conserved Domains (3) summary
      smart00225
      Location:144 → 242
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:258 → 359
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:135 → 239
      BTB; BTB/POZ domain

    3. NM_132515.3 → NP_572743.1  transport and golgi organization 10, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572743.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K187
      Related
      FBpp0073398
      Conserved Domains (3) summary
      smart00225
      Location:144 → 242
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:258 → 359
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:135 → 239
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K187 Q7K187

    Gene LinkOut

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