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    koko kokopelli [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 14462485, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kokoprovided by FlyBase
    Official Full Name
    kokopelliprovided by FlyBase
    Primary source
    FLYBASE:FBgn0264816
    Locus tag
    Dmel_CG44010
    See related
    AllianceGenome:FB:FBgn0264816
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31232; CG44010; CG7683; Dmel\CG44010
    Old locus tag
    Dmel_CG31232
    Summary
    Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in syndactyly-telecanthus-anogenital and renal malformations syndrome. Orthologous to human CCNQ (cyclin Q). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See koko in Genome Data Viewer
    Location:
    91A6-91A6; 3-63 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18403026..18404726)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14228748..14230448)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Vacuolar H[+] ATPase 100kD subunit 2 Neighboring gene Vesicle transport through interaction with t-SNAREs 1b Neighboring gene WD repeat domain 37 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes. Palgi M, et al. BMC Genomics, 2012 Apr 11. PMID 22494833, Free PMC Article
    2. Dissecting the lean, mean, breeding machine. Nurminsky DI. Fly (Austin), 2007 Mar-Apr. PMID 19378459
    3. Photoperiod-Dependent Expression of MicroRNA in Drosophila. Pegoraro M, et al. Int J Mol Sci, 2022 Apr 29. PMID 35563325, Free PMC Article
    4. Transcriptomes of lineage-specific Drosophila neuroblasts profiled by genetic targeting and robotic sorting. Yang CP, et al. Development, 2016 Feb 1. PMID 26700685, Free PMC Article
    5. Gliogenesis in Drosophila: genome-wide analysis of downstream genes of glial cells missing in the embryonic nervous system. Egger B, et al. Development, 2002 Jul. PMID 12091301

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    kokopelli
    Names
    CG44010-PB
    CG44010-PC
    CG44010-PD
    CG44010-PE
    koko-PB
    koko-PC
    koko-PD
    koko-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18403026..18404726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169814.3 → NP_732341.1  kokopelli, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732341.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU34, Q8IG98, Q9VE72
      Conserved Domains (1) summary
      pfam00134
      Location:6 → 144
      Cyclin_N; Cyclin, N-terminal domain

    2. NM_169812.3 → NP_732339.1  kokopelli, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732339.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU34, Q8IG98, Q9VE72
      Conserved Domains (1) summary
      pfam00134
      Location:6 → 144
      Cyclin_N; Cyclin, N-terminal domain

    3. NM_169813.3 → NP_732340.1  kokopelli, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732340.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU34, Q8IG98, Q9VE72
      Conserved Domains (1) summary
      pfam00134
      Location:6 → 144
      Cyclin_N; Cyclin, N-terminal domain

    4. NM_169811.3 → NP_732338.1  kokopelli, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732338.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YU34, Q8IG98, Q9VE72
      Conserved Domains (1) summary
      pfam00134
      Location:6 → 144
      Cyclin_N; Cyclin, N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7YU34 Q7YU34
    Q8IG98 Q8IG98
    Q9VE72 Q9VE72

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials