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    Blos2 Biogenesis of lysosome-related organelles complex 1, subunit 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39234, updated on 9-Dec-2024

    Summary

    Official Symbol
    Blos2provided by FlyBase
    Official Full Name
    Biogenesis of lysosome-related organelles complex 1, subunit 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0036118
    Locus tag
    Dmel_CG14145
    See related
    AllianceGenome:FB:FBgn0036118
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    blos2; BLOS2; CG14145; DmBlos2; Dmel\CG14145; NP_648427
    Summary
    Enables protein homodimerization activity. Involved in autophagosome-lysosome fusion. Predicted to be part of BLOC-1 complex; BORC complex; and gamma-tubulin complex. Orthologous to human BLOC1S2 (biogenesis of lysosomal organelles complex 1 subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Blos2 in Genome Data Viewer
    Location:
    68A3-68A3; 3-34 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11061571..11062215)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11054671..11055315)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45119 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Suppressor of Under-Replication

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables gamma-tubulin binding  
    enables protein binding PubMed 
    enables protein homodimerization activity PubMed 
    Process Evidence Code Pubs
    involved_in autophagosome-lysosome fusion PubMed 
    involved_in endosomal transport  
    involved_in lysosome localization  
    Component Evidence Code Pubs
    part_of BLOC-1 complex  
    part_of BLOC-1 complex PubMed 
    part_of BORC complex  
    part_of gamma-tubulin complex  

    General protein information

    Preferred Names
    biogenesis of lysosome-related organelles complex 1, subunit 2
    Names
    BLOC-1 subunit 2
    Blos2-PA
    CG14145-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11061571..11062215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140170.2 → NP_648427.1  biogenesis of lysosome-related organelles complex 1, subunit 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648427.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VTE0
      UniProtKB/TrEMBL
      A0A1B2AKW7
      Related
      FBpp0075932
      Conserved Domains (1) summary
      pfam10046
      Location:51 → 145
      BLOC1_2; Biogenesis of lysosome-related organelles complex-1 subunit 2
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