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    Rpl39 ribosomal protein L39 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25347, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpl39provided by RGD
    Official Full Name
    ribosomal protein L39provided by RGD
    Primary source
    RGD:3593
    See related
    EnsemblRapid:ENSRNOG00000043348 AllianceGenome:RGD:3593
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide; cytoplasmic translation; and innate immune response in mucosa. Part of cytosolic large ribosomal subunit. Orthologous to human RPL39 (ribosomal protein L39). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 4872.6), Thymus (RPKM 4511.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpl39 in Genome Data Viewer
    Location:
    Xq35
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (121192901..121195896, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (116327216..116330211, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (123705241..123707257, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene septin 6 Neighboring gene sosondowah ankyrin repeat domain family member D Neighboring gene small nucleolar RNA SNORA69 Neighboring gene UPF3B, regulator of nonsense mediated mRNA decay Neighboring gene NFKB activating protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in innate immune response in mucosa ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein eL39
    Names
    60S ribosomal protein L39

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012875.4NP_037007.1  large ribosomal subunit protein eL39

      See identical proteins and their annotated locations for NP_037007.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/Swiss-Prot
      P62893
      UniProtKB/TrEMBL
      A6JMH4
      Related
      ENSRNOP00000103559.1, ENSRNOT00000137267.1
      Conserved Domains (1) summary
      pfam00832
      Location:950
      Ribosomal_L39; Ribosomal L39 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      121192901..121195896 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)