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    dpr16 defective proboscis extension response 16 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40619, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpr16provided by FlyBase
    Official Full Name
    defective proboscis extension response 16provided by FlyBase
    Primary source
    FLYBASE:FBgn0037295
    Locus tag
    Dmel_CG12591
    See related
    AllianceGenome:FB:FBgn0037295
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12591; CT34444; Dmel\CG12591; Dpr-16; Dpr16; mdcds_51595
    Summary
    Involved in synapse organization. Predicted to be located in extracellular region. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dpr16 in Genome Data Viewer
    Location:
    82F1-82F3; 3-47.5 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5150908..5170121)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (976630..995843)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Rab geranylgeranyltransferase subunit alpha Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene canoe Neighboring gene small nuclear RNA U4atac Neighboring gene Proteasome beta2 subunit-related 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster. Cridland JM, et al. Genetics, 2023 May 4. PMID 36869688, Free PMC Article
    2. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article
    3. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
    4. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
    5. A transcriptional network associated with natural variation in Drosophila aggressive behavior. Edwards AC, et al. Genome Biol, 2009. PMID 19607677, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 5167578-5169210 mobile_element_type = transposon:Tc1{}1216

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    defective proboscis extension response 16
    Names
    CG12591-PB
    CG12591-PC
    dpr16-PB
    dpr16-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5150908..5170121
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300240.1 → NP_001287169.1  defective proboscis extension response 16, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287169.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGN7
      Conserved Domains (3) summary
      cd00096
      Location:358 → 439
      Ig; Immunoglobulin domain
      smart00410
      Location:352 → 447
      IG_like; Immunoglobulin like
      cl11960
      Location:298 → 338
      Ig; Immunoglobulin domain

    2. NM_001043212.3 → NP_001036677.1  defective proboscis extension response 16, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036677.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KIC0
      Conserved Domains (3) summary
      cd00096
      Location:313 → 394
      Ig; Immunoglobulin domain
      smart00410
      Location:307 → 402
      IG_like; Immunoglobulin like
      cl11960
      Location:253 → 293
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LGN7 A0A0B4LGN7
    Q0KIC0 Q0KIC0
    Q8MT24 Q8MT24

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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