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    dpt-1 Dipeptidyl peptidase 3 [ Caenorhabditis elegans ]

    Gene ID: 172631, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dpt-1
    Official Full Name
    Dipeptidyl peptidase 3
    Primary source
    WormBase:WBGene00008532
    Locus tag
    CELE_F02E9.9
    See related
    AllianceGenome:WB:WBGene00008532
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Orthologous to human DPP3 (dipeptidyl peptidase 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dpt-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    14
    Sequence:
    Chromosome: I; NC_003279.8 (8429934..8435865, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Paired amphipathic helix protein sin-3 Neighboring gene Oxidative stress-responsive serine-rich protein 1 Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene pseudo Neighboring gene Superoxide dismutase [Mn] 1, mitochondrial Neighboring gene Uncharacterized protein Neighboring gene BAG domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dipeptidyl-peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Dipeptidyl peptidase 3
    NP_001366938.1
    • Confirmed by transcript evidence
    NP_001367133.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8429934..8435865 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380843.2 → NP_001366938.1  Dipeptidyl peptidase 3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U3K7
      Conserved Domains (1) summary
      pfam03571
      Location:144 → 687
      Peptidase_M49; Peptidase family M49

    2. NM_001380842.1 → NP_001367133.1  Dipeptidyl peptidase 3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECW7
      Conserved Domains (1) summary
      pfam03571
      Location:182 → 725
      Peptidase_M49; Peptidase family M49
    Nucleotide Protein
    Heading Accession and Version

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