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    oppC murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945810, updated on 3-Dec-2024

    Summary

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    Official Symbol
    oppC
    Official Full Name
    murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC
    Primary source
    ECOCYC:EG10676
    Locus tag
    b1245
    See related
    ASAP:ABE-0004176
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1239
    Summary
    OppC is an integral membrane component of the oligopeptide ABC transporter and the murein tripeptide ABC transporter. [More information is available at EcoCyc: EG10676].
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    Genomic context

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    Sequence:
    NC_000913.3 (1303834..1304742)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene oligopeptide ABC transporter periplasmic binding protein Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppB Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppD Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppF Neighboring gene DUF440 domain-containing protein YciU

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic organization of the oligopeptide permease (opp) locus of Salmonella typhimurium and Escherichia coli. Hogarth BG, et al. J Bacteriol, 1983 Mar. PMID 6338001, Free PMC Article
    2. The structural basis of sequence-independent peptide binding by OppA protein. Tame JR, et al. Science, 1994 Jun 10. PMID 8202710
    3. Genetic analysis of Escherichia coli oligopeptide transport mutants. Andrews JC, et al. J Bacteriol, 1985 Feb. PMID 2981814, Free PMC Article
    4. The periplasmic murein peptide-binding protein MppA is a negative regulator of multiple antibiotic resistance in Escherichia coli. Li H, et al. J Bacteriol, 1999 Aug. PMID 10438753, Free PMC Article
    5. Structure determination of OppA at 2.3 A resolution using multiple-wavelength anomalous dispersion methods. Glover ID, et al. Acta Crystallogr D Biol Crystallogr, 1995 Jan 1. PMID 15299334

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In vivo OppC functionality was determined by constructing an OppC gene deletion strain. OppC was shown to be essential for peptide uptake, and non-essential for cell viability
      Title: Detection of soluble expression and in vivo interactions of the inner membrane protein OppC using green fluorescent protein.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables peptidoglycan peptide transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in oligopeptide import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within peptidoglycan-associated peptide transport EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tripeptide import across plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC
    NP_415761.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1303834..1304742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415761.1 murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415761.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H3PMS2, A0A221BH49, A0A376K2C3, A0A5B9AKE3, A0AAN4NX40
      Conserved Domains (1) summary
      PRK15406
      Location:1 → 302
      PRK15406; oligopeptide ABC transporter permease OppC; Provisional
    Nucleotide Protein
    Heading Accession and Version

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