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    AMF1 Amf1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854560, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AMF1
    Official Full Name
    Amf1p
    Primary source
    SGD:S000005905
    Locus tag
    YOR378W
    See related
    AllianceGenome:SGD:S000005905; FungiDB:YOR378W; VEuPathDB:YOR378W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables ammonium channel activity. Involved in ammonium transmembrane transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See AMF1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (1049511..1051058)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene alcohol O-acetyltransferase Neighboring gene Rdr1p Neighboring gene ferric-chelate reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Roles of ATR1 paralogs YMR279c and YOR378w in boron stress tolerance. Bozdag GO, et al. Biochem Biophys Res Commun, 2011 Jun 17. PMID 21621519
    2. Soybean SAT1 (Symbiotic Ammonium Transporter 1) encodes a bHLH transcription factor involved in nodule growth and NH4+ transport. Chiasson DM, et al. Proc Natl Acad Sci U S A, 2014 Apr 1. PMID 24707045, Free PMC Article
    3. Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Kaya A, et al. Mol Cell Biol, 2009 Jul. PMID 19414602, Free PMC Article
    4. Genome-Wide Studies of Rho5-Interacting Proteins That Are Involved in Oxidant-Induced Cell Death in Budding Yeast. Singh K, et al. G3 (Bethesda), 2019 Mar 7. PMID 30670610, Free PMC Article
    5. Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin. Boettner DR, et al. Mol Biol Cell, 2011 Oct. PMID 21849475, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ammonium channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ammonium transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ammonium transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Amf1p
    NP_015023.1
    • Low affinity NH4+ transporter; member of the DHA2 family of drug:H+ anti porters; putative paralog of ATR1; but not required for boron tolerance; non-essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      1049511..1051058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183798.1 → NP_015023.1  TPA: Amf1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015023.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W371, Q08902
      UniProtKB/TrEMBL
      A6ZPK6, B5VSQ2, C7GVG8, N1NXK2
      Conserved Domains (1) summary
      cd17476
      Location:48 → 493
      MFS_Amf1_MDR_like; Saccharomyces cerevisiae low affinity ammonium transporter Amf1p/YOR378W, aminotriazole resistance protein Atr1p, and similar transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08902.1

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