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    MRP20 mitochondrial 54S ribosomal protein YmL41 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852014, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRP20
    Official Full Name
    mitochondrial 54S ribosomal protein YmL41
    Primary source
    SGD:S000002813
    Locus tag
    YDR405W
    See related
    AllianceGenome:SGD:S000002813; FungiDB:YDR405W; VEuPathDB:YDR405W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uL23m
    Summary
    A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL23 (mitochondrial ribosomal protein L23). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRP20 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1277646..1278437)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Dit1p Neighboring gene DNA-directed RNA polymerase II subunit RPB7 Neighboring gene ATP-binding cassette multidrug transporter PDR15 Neighboring gene Trs120p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and function of MRP20 and MRP49, the nuclear genes for two proteins of the 54 S subunit of the yeast mitochondrial ribosome. Fearon K, et al. J Biol Chem, 1992 Mar 15. PMID 1544898
    2. Yeast Oxa1 interacts with mitochondrial ribosomes: the importance of the C-terminal region of Oxa1. Jia L, et al. EMBO J, 2003 Dec 15. PMID 14657017, Free PMC Article
    3. Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly. Jia L, et al. Eukaryot Cell, 2009 Nov. PMID 19783770, Free PMC Article
    4. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. Gruschke S, et al. J Biol Chem, 2010 Jun 18. PMID 20404317, Free PMC Article
    5. Cbp3 and Cbp6 are dispensable for synthesis regulation of cytochrome b in yeast mitochondria. García-Guerrero AE, et al. J Biol Chem, 2018 Apr 13. PMID 29475949, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The carboxy-terminal mitochondrial-specific domain of Mrp20 was found to have a crucial role in the assembly of the ribosomes.
      Title: Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL41
    NP_010693.3
    • Mitochondrial ribosomal protein of the large subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1277646..1278437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180713.3 → NP_010693.3  TPA: mitochondrial 54S ribosomal protein YmL41 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010693.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT37, P32387
      UniProtKB/TrEMBL
      A6ZZ04, B3LFP7, B5VGT5, C7GSB9, C8Z5W8, G2WBE3, N1PAJ5
      Conserved Domains (1) summary
      pfam00276
      Location:104 → 166
      Ribosomal_L23; Ribosomal protein L23
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32387.1

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