U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MHP1 Mhp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853408, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MHP1
    Official Full Name
    Mhp1p
    Primary source
    SGD:S000003578
    Locus tag
    YJL042W
    See related
    AllianceGenome:SGD:S000003578; FungiDB:YJL042W; VEuPathDB:YJL042W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of cytoskeleton. Involved in fungal-type cell wall organization and negative regulation of microtubule depolymerization. Located in microtubule. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MHP1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (361249..365445)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene GTPase-activating protein GYP6 Neighboring gene uncharacterized protein Neighboring gene FG-nucleoporin NSP1 Neighboring gene Nup192p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Quality control and substrate-dependent downregulation of the nutrient transporter Fur4. Keener JM, et al. Traffic, 2013 Apr. PMID 23305501, Free PMC Article
    2. Multiple copies of PBS2, MHP1 or LRE1 produce glucanase resistance and other cell wall effects in Saccharomyces cerevisiae. Lai MH, et al. Yeast, 1997 Mar 15. PMID 9090049
    3. Effect of microtubule-associated protein MHP1 on microtubule assembly and cell cycle progression in Saccharomyces cerevisiae. Irminger-Finger I, et al. Cell Struct Funct, 1998 Aug. PMID 9855114
    4. MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function. Irminger-Finger I, et al. J Cell Biol, 1996 Dec. PMID 8947554, Free PMC Article
    5. A P4-ATPase protein interaction network reveals a link between aminophospholipid transport and phosphoinositide metabolism. Puts CF, et al. J Proteome Res, 2010 Feb 5. PMID 19968326

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of microtubule depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Mhp1p
    NP_012493.1
    • Microtubule-associated protein involved in microtubule organization; involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      361249..365445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181475.1 → NP_012493.1  TPA: Mhp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012493.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWE2, P43638
      UniProtKB/TrEMBL
      A6ZPT5, N1P8I9
      Conserved Domains (1) summary
      cl39015
      Location:832 → 1015
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43638.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools