Y62E10A.6 NADPH:adrenodoxin oxidoreductase, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y62E10A.6
Official Full Name: NADPH:adrenodoxin oxidoreductase, mitochondrial
Primary source: WormBase:WBGene00013376
Locus tag: CELE_Y62E10A.6
See related: AllianceGenome:WB:WBGene00013376
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable NADPH-adrenodoxin reductase activity. Predicted to be involved in NADPH oxidation and steroid biosynthetic process. Predicted to be active in mitochondrion. Orthologous to human FDXR (ferredoxin reductase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Y62E10A.6 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 7

Sequence:: Chromosome: IV; NC_003282.8 (13371999..13377383)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS4-194 (e-PCR)
- UniSTS:242185

Y62E10A.f (e-PCR)
- UniSTS:324105

Y62E10A.e (e-PCR)
- UniSTS:324457

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables NADPH-adrenodoxin reductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables NADPH-adrenodoxin reductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in NADPH oxidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in cholesterol metabolic process	IEA Inferred from Electronic Annotation more info
involved_in steroid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: NADPH:adrenodoxin oxidoreductase, mitochondrial

NP_502573.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

13371999..13377383

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070172.4 → NP_502573.1 NADPH:adrenodoxin oxidoreductase, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_502573.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9U1X0

Conserved Domains (2) summary

PLN02852
Location:23 → 451

PLN02852; ferredoxin-NADP+ reductase

pfam13450
Location:30 → 73

NAD_binding_8; NAD(P)-binding Rossmann-like domain