Upk3bl uroplakin 3B-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Upk3blprovided by MGI
Official Full Name: uroplakin 3B-likeprovided by MGI
Primary source: MGI:MGI:1916915
See related: Ensembl:ENSMUSG00000006143 AllianceGenome:MGI:1916915
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Upk3bl1; 2310043J07Rik
Summary: Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be active in membrane. Is expressed in genitourinary system. Orthologous to several human genes including UPK3BL1 (uroplakin 3B like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in testis adult (RPKM 15.0), CNS E18 (RPKM 1.3) and 2 other tissues See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 5 G2; 5 75.72 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (136086114..136105549)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (136057259..136076695)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info
enables peroxidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in cellular oxidant detoxification	IEA Inferred from Electronic Annotation more info
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: uroplakin-3b-like protein 1

Names: uroplakin-3-like protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001359361.1 → NP_001346290.1 uroplakin-3b-like protein 1 isoform 2 precursor

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 3' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.

Source sequence(s)

AC087420, BC115564

UniProtKB/Swiss-Prot

A0AUM6, Q4KL12, Q9D701

UniProtKB/TrEMBL

F6X493

Related

ENSMUSP00000123311.3, ENSMUST00000156530.8

Conserved Domains (1) summary

cl06408
Location:28 → 201

UP_III_II; Uroplakin IIIb, IIIa and II
NM_027158.1 → NP_081434.1 uroplakin-3b-like protein 1 isoform 1 precursor

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes the longer isoform (1).

Source sequence(s)

BC115563, BX638176

Consensus CDS

CCDS51665.1

UniProtKB/TrEMBL

F6X493, F8WJ60

Related

ENSMUSP00000006303.5, ENSMUST00000006303.11

Conserved Domains (1) summary

cl06408
Location:28 → 201

UP_III_II; Uroplakin IIIb, IIIa and II

RNA

NR_153102.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (3) contains an alternate exon in the 3' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC087420

Related

ENSMUST00000111137.8