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    pwn pawn [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44011, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pwnprovided by FlyBase
    Official Full Name
    pawnprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003174
    Locus tag
    Dmel_CG11101
    See related
    AllianceGenome:FB:FBgn0003174
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11101; CT31067; Dmel\CG11101; l(2)pwn
    Summary
    Predicted to enable calcium ion binding activity. Involved in chaeta morphogenesis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See pwn in Genome Data Viewer
    Location:
    43A3-43A3; 2-55 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7282572..7300806)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3170077..3188311)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Bromodomain-containing protein, 140kD Neighboring gene Inner centromere protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45129 Neighboring gene Down syndrome cell adhesion molecule 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Compartments in the wing of Drosophila: a study of the engrailed gene. Lawrence PA, et al. Dev Biol, 1976 Jun. PMID 1278589
    2. Cell proliferation patterns in the wing imaginal disc of Drosophila. González-Gaitán M, et al. Mech Dev, 1994 Jun. PMID 7918103
    3. Clonal analysis in hybrids between Drosophila melanogaster and Drosophila simulans. Sanchez L, et al. Rouxs Arch Dev Biol, 1994 Dec. PMID 28305934
    4. Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity. Struhl G, et al. Development, 2012 Oct. PMID 22949620, Free PMC Article
    5. Cell interactions and planar polarity in the abdominal epidermis of Drosophila. Lawrence PA, et al. Development, 2004 Oct. PMID 15329345

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chaeta morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pawn
    Names
    CG11101-PB
    CG11101-PC
    N-like
    pwn-PB
    pwn-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7282572..7300806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136423.2 → NP_610267.2  pawn, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610267.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6W9
      Conserved Domains (3) summary
      smart00179
      Location:1026 → 1075
      EGF_CA; Calcium-binding EGF-like domain
      pfam07974
      Location:1074 → 1109
      EGF_2; EGF-like domain
      pfam15420
      Location:1124 → 1165
      Abhydrolase_9_N; Alpha/beta-hydrolase family N-terminus

    2. NM_001273834.1 → NP_001260763.1  pawn, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260763.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEW8
      Conserved Domains (3) summary
      smart00179
      Location:1004 → 1053
      EGF_CA; Calcium-binding EGF-like domain
      pfam07974
      Location:1052 → 1087
      EGF_2; EGF-like domain
      pfam15420
      Location:1102 → 1143
      Abhydrolase_9_N; Alpha/beta-hydrolase family N-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KEW8 A0A0B4KEW8
    A1Z6W9 A1Z6W9

    Gene LinkOut

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