sec-10 Exocyst complex component 5 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: sec-10
Official Full Name: Exocyst complex component 5
Primary source: WormBase:WBGene00016376
Locus tag: CELE_C33H5.9
See related: AllianceGenome:WB:WBGene00016376
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be located in cytoplasm. Predicted to be part of exocyst. Is expressed in several structures, including coelomocyte; excretory canal; head neurons; intestine; and reproductive system. Orthologous to human EXOC5 (exocyst complex component 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sec-10 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 4

Sequence:: Chromosome: IV; NC_003282.8 (7779381..7782499, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SEC-10 coordinates with RAB-10 and microtubules to form the endosomal tubular network for efficient recycling of particular clathrin-independent endocytic cargoes.
Title: SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C33H5.9 (e-PCR)
- UniSTS:308703

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in Golgi to plasma membrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in exocytosis	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of exocyst	IBA Inferred from Biological aspect of Ancestor more info
part_of exocyst	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: Exocyst complex component 5

NP_501283.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

7779381..7782499 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_068882.8 → NP_501283.2 Exocyst complex component 5 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18406

Conserved Domains (1) summary

pfam07393
Location:91 → 703

Sec10; Exocyst complex component Sec10