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    Prosbeta4R1 Proteasome beta4 subunit-related 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33449, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prosbeta4R1provided by FlyBase
    Official Full Name
    Proteasome beta4 subunit-related 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031442
    Locus tag
    Dmel_CG17301
    See related
    AllianceGenome:FB:FBgn0031442
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT30033; beta4R1; CG17301; Dmel\CG17301
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in cytosol and nucleus. Orthologous to human PSMB2 (proteasome 20S subunit beta 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Prosbeta4R1 in Genome Data Viewer
    Location:
    23A2-23A2; 2-7 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2653046..2653926)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2653046..2653926)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Proteasome beta4 subunit-related 2 Neighboring gene Odorant receptor 23a Neighboring gene TBP-related factor 4

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in cytosol  
    is_active_in nucleus  
    part_of proteasome core complex  
    part_of proteasome core complex, beta-subunit complex  
    part_of proteasome core complex, beta-subunit complex  

    General protein information

    Preferred Names
    proteasome beta4 subunit-related 1
    Names
    CG17301-PA
    Prosbeta4R1-PA
    proteasome beta4R1 subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2653046..2653926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134854.3 → NP_608698.2  proteasome beta4 subunit-related 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608698.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8U1, Q9VQE4
      Related
      FBpp0077381
      Conserved Domains (2) summary
      COG0638
      Location:1 → 204
      PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
      cd03758
      Location:1 → 193
      proteasome_beta_type_2; proteasome beta type-2 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
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