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    hyfG hydrogenase 4 catalytic subunit HyfG [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946964, updated on 3-Dec-2024

    Summary

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    Official Symbol
    hyfG
    Official Full Name
    hydrogenase 4 catalytic subunit HyfG
    Primary source
    ECOCYC:G7304
    Locus tag
    b2487
    See related
    ASAP:ABE-0008194
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2483
    Summary
    This is the larger of the two catalytic subunits. [More information is available at EcoCyc: G7304].
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    Genomic context

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    Sequence:
    NC_000913.3 (2608487..2610154)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase 4 component D Neighboring gene hydrogenase 4 component E Neighboring gene hydrogenase 4 component F Neighboring gene hydrogenase 4 component H Neighboring gene hydrogenase 4 catalytic subunit HyfI Neighboring gene putative hydrogenase 4 assembly protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional control of hydrogen production during mixed carbon fermentation by hydrogenases 4 (hyf) and 3 (hyc) in Escherichia coli. Trchounian K. Gene, 2012 Sep 10. PMID 22771922
    2. Participation of hyf-encoded hydrogenase 4 in molecular hydrogen release coupled with proton-potassium exchange in Escherichia coli. Bagramyan K, et al. Membr Cell Biol, 2001. PMID 11817571
    3. Phosphorylation of ribosomal proteins in HeLa cells infected with vaccinia virus. Kaerlein M, et al. Nature, 1976 Jan 15. PMID 1246353
    4. Expression and regulation of a silent operon, hyf, coding for hydrogenase 4 isoenzyme in Escherichia coli. Self WT, et al. J Bacteriol, 2004 Jan. PMID 14702328, Free PMC Article
    5. A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system. Andrews SC, et al. Microbiology (Reading), 1997 Nov. PMID 9387241

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADH dehydrogenase (ubiquinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal cluster binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nickel cation binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables quinone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in anaerobic electron transport chain NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in anaerobic respiration NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in formate oxidation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in glucose catabolic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of [Ni-Fe] hydrogenase complex RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of formate dehydrogenase complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydrogenase 4 catalytic subunit HyfG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2608487..2610154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416982.1 hydrogenase 4 catalytic subunit HyfG [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416982.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FYA6
      Conserved Domains (2) summary
      COG3261
      Location:174 → 538
      HycE2; Ni,Fe-hydrogenase III large subunit [Energy production and conversion]
      COG3262
      Location:5 → 169
      HycE1; Ni,Fe-hydrogenase III component G [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version

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