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    semo-1 Methanethiol oxidase [ Caenorhabditis elegans ]

    Gene ID: 178360, updated on 9-Dec-2024

    Summary

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    Official Symbol
    semo-1
    Official Full Name
    Methanethiol oxidase
    Primary source
    WormBase:WBGene00012538
    Locus tag
    CELE_Y37A1B.5
    See related
    AllianceGenome:WB:WBGene00012538
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables methanethiol oxidase activity. Is expressed in hypodermis. Orthologous to human SELENBP1 (selenium binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See semo-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (14051200..14056717)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Transposase Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selenium-Enriched E. coli Bacteria Mitigate the Age-Associated Degeneration of Cholinergic Neurons in C. elegans. Zytner P, et al. Antioxidants (Basel), 2024 Apr 20. PMID 38671939, Free PMC Article
    2. SEMO-1, a novel methanethiol oxidase in Caenorhabditis elegans, is a pro-aging factor conferring selective stress resistance. Philipp TM, et al. Biofactors, 2022 May. PMID 35316559
    3. Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase. Philipp TM, et al. Redox Biol, 2023 Sep. PMID 37437449, Free PMC Article
    4. A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. Köhnlein K, et al. Redox Biol, 2020 Jan. PMID 31557719, Free PMC Article
    5. Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans. Wang X, et al. EMBO J, 2022 Apr 19. PMID 35253240, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
      Title: A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methanethiol oxidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables selenium binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Methanethiol oxidase
    NP_001255777.1
    • Partially confirmed by transcript evidence
    NP_001255778.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      14051200..14056717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268848.2 → NP_001255777.1  Methanethiol oxidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255777.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXF9
      Conserved Domains (1) summary
      pfam05694
      Location:9 → 471
      SBP56; 56kDa selenium binding protein (SBP56)

    2. NM_001268849.3 → NP_001255778.1  Methanethiol oxidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255778.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3NQ99
      Conserved Domains (1) summary
      pfam05694
      Location:1 → 164
      SBP56; 56kDa selenium binding protein (SBP56)

    RNA

    1. NR_131636.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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