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    pod-1 Coronin-7 [ Caenorhabditis elegans ]

    Gene ID: 176784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pod-1
    Official Full Name
    Coronin-7
    Primary source
    WormBase:WBGene00004075
    Locus tag
    CELE_Y76A2B.1
    See related
    AllianceGenome:WB:WBGene00004075
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables actin filament binding activity. Located in cell cortex of cell tip and cleavage furrow. Orthologous to human CORO7 (coronin 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pod-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (13514941..13524121, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene SPK domain-containing protein Neighboring gene DNA mismatch repair protein S5 domain-containing protein Neighboring gene tRNA Neighboring gene tRNA Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Actin filament debranching regulates cell polarity during cell migration and asymmetric cell division. Xie C, et al. Proc Natl Acad Sci U S A, 2021 Sep 14. PMID 34507987, Free PMC Article
    2. Pod-2, along with pod-1, defines a new class of genes required for polarity in the early Caenorhabditis elegans embryo. Tagawa A, et al. Dev Biol, 2001 May 15. PMID 11336504
    3. Isolation of actin-associated proteins from Caenorhabditis elegans oocytes and their localization in the early embryo. Aroian RV, et al. EMBO J, 1997 Apr 1. PMID 9130699, Free PMC Article
    4. Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. Rappleye CA, et al. BMC Dev Biol, 2003 Oct 3. PMID 14527340, Free PMC Article
    5. The BTB protein MEL-26 promotes cytokinesis in C. elegans by a CUL-3-independent mechanism. Luke-Glaser S, et al. Curr Biol, 2005 Sep 20. PMID 16169482

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cleavage furrow IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Coronin-7
    NP_001263733.1
    • Confirmed by transcript evidence
    NP_001263734.1
    • Confirmed by transcript evidence
    NP_001263735.1
    • Confirmed by transcript evidence
    NP_001417849.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13514941..13524121 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276804.3 → NP_001263733.1  Coronin-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263733.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8FE00
      Conserved Domains (5) summary
      PTZ00421
      Location:555 → 985
      PTZ00421; coronin; Provisional
      pfam08953
      Location:7 → 62
      DUF1899; Domain of unknown function (DUF1899)
      pfam16300
      Location:340 → 383
      WD40_4; Type of WD40 repeat
      sd00039
      Location:632 → 676
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:672 → 747
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001430920.1 → NP_001417849.1  Coronin-7 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDS2

    3. NM_001276805.5 → NP_001263734.1  Coronin-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263734.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8F7Z0
      Conserved Domains (5) summary
      PTZ00421
      Location:599 → 1029
      PTZ00421; coronin; Provisional
      pfam08953
      Location:7 → 106
      DUF1899; Domain of unknown function (DUF1899)
      pfam16300
      Location:384 → 427
      WD40_4; Type of WD40 repeat
      sd00039
      Location:676 → 720
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:716 → 791
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. NM_001276806.2 → NP_001263735.1  Coronin-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263735.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8ESK9
      Conserved Domains (5) summary
      PTZ00421
      Location:599 → 1029
      PTZ00421; coronin; Provisional
      pfam08953
      Location:7 → 106
      DUF1899; Domain of unknown function (DUF1899)
      pfam16300
      Location:384 → 427
      WD40_4; Type of WD40 repeat
      sd00039
      Location:676 → 720
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:716 → 791
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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