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    sec-16A.2 Protein transport protein sec16 [ Caenorhabditis elegans ]

    Gene ID: 181084, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sec-16A.2
    Official Full Name
    Protein transport protein sec16
    Primary source
    WormBase:WBGene00017419
    Locus tag
    CELE_F13B9.1
    See related
    AllianceGenome:WB:WBGene00017419
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in Golgi organization and protein localization to endoplasmic reticulum exit site. Predicted to be located in Golgi membrane and endoplasmic reticulum. Predicted to be active in ER to Golgi transport vesicle membrane and endoplasmic reticulum exit site. Orthologous to several human genes including SEC16A (SEC16 homolog A, endoplasmic reticulum export factor). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sec-16A.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Sequence:
    Chromosome: X; NC_003284.9 (8287249..8294519)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ground-like domain-containing protein Neighboring gene Mediator of RNA polymerase II transcription subunit 27 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
    2. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
    3. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    4. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    5. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in COPII vesicle coating IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein localization to endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ER to Golgi transport vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum exit site IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein transport protein sec16
    NP_001024557.1
    • Partially confirmed by transcript evidence
    NP_001360731.1
    • Partially confirmed by transcript evidence
    NP_001360732.1
    • Confirmed by transcript evidence
    NP_001360733.1
    • Confirmed by transcript evidence
    NP_509399.2
    • Confirmed by transcript evidence
    NP_509400.3
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8287249..8294519
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373387.3 → NP_001360731.1  Protein transport protein sec16 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IM30
      Conserved Domains (3) summary
      cd09233
      Location:903 → 1258
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      PRK10263
      Location:1328 → 1459
      PRK10263; DNA translocase FtsK; Provisional
      pfam09507
      Location:230 → 438
      CDC27; DNA polymerase subunit Cdc27

    2. NM_076999.9 → NP_509400.3  Protein transport protein sec16 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509400.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZQ8
      Conserved Domains (1) summary
      cd09233
      Location:925 → 1280
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

    3. NM_001029386.5 → NP_001024557.1  Protein transport protein sec16 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024557.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZQ9
      Conserved Domains (1) summary
      cd09233
      Location:903 → 1258
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

    4. NM_076998.5 → NP_509399.2  Protein transport protein sec16 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509399.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZV3
      Conserved Domains (1) summary
      cd09233
      Location:903 → 1258
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16

    5. NM_001373388.2 → NP_001360732.1  Protein transport protein sec16 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IKE4
      Conserved Domains (4) summary
      cd09233
      Location:862 → 1217
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      PHA03247
      Location:1353 → 1568
      PHA03247; large tegument protein UL36; Provisional
      PRK10263
      Location:1287 → 1418
      PRK10263; DNA translocase FtsK; Provisional
      pfam04747
      Location:206 → 398
      DUF612; Protein of unknown function, DUF612

    6. NM_001373389.3 → NP_001360733.1  Protein transport protein sec16 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IKA6
      Conserved Domains (3) summary
      cd09233
      Location:862 → 1217
      ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16
      PRK10263
      Location:1287 → 1418
      PRK10263; DNA translocase FtsK; Provisional
      pfam04747
      Location:206 → 398
      DUF612; Protein of unknown function, DUF612
    Nucleotide Protein
    Heading Accession and Version

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