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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_033840.1 RefSeqGene
- Range
-
5001..68763
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_789
mRNA and Protein(s)
-
NM_006231.4 → NP_006222.2 DNA polymerase epsilon catalytic subunit A
See identical proteins and their annotated locations for NP_006222.2
Status: REVIEWED
- Source sequence(s)
-
BC011376, CX782956, L09561
- Consensus CDS
-
CCDS9278.1
- UniProtKB/Swiss-Prot
- Q07864, Q13533, Q86VH9
- UniProtKB/TrEMBL
-
Q9Y5S4
- Related
- ENSP00000322570.5, ENST00000320574.10
- Conserved Domains (3) summary
-
- cd05779
Location:268 → 471
- DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase
- cd05535
Location:531 → 1153
- POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...
- pfam08490
Location:1538 → 1925
- DUF1744; Domain of unknown function (DUF1744)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12 Reference GRCh38.p14 Primary Assembly
- Range
-
132623762..132687342 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011534802.4 → XP_011533104.1 DNA polymerase epsilon catalytic subunit A isoform X5
- Conserved Domains (2) summary
-
- cl10023
Location:12 → 149
- POLBc; DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic ...
- pfam08490
Location:525 → 921
- DUF1744; Domain of unknown function (DUF1744)
-
XM_011534795.4 → XP_011533097.1 DNA polymerase epsilon catalytic subunit A isoform X1
- UniProtKB/TrEMBL
-
Q9Y5S4
- Conserved Domains (4) summary
-
- cd05779
Location:268 → 471
- DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase
- cd05535
Location:531 → 1153
- POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...
- COG0417
Location:99 → 1165
- PolB; DNA polymerase elongation subunit (family B) [Replication, recombination and repair]
- pfam08490
Location:1529 → 1925
- DUF1744; Domain of unknown function (DUF1744)
-
XM_011534797.4 → XP_011533099.1 DNA polymerase epsilon catalytic subunit A isoform X2
- UniProtKB/TrEMBL
-
Q9UNF3
- Conserved Domains (4) summary
-
- cd05779
Location:3 → 164
- DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase
- cd05535
Location:224 → 846
- POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...
- smart00486
Location:8 → 563
- POLBc; DNA polymerase type-B family
- pfam08490
Location:1222 → 1618
- DUF1744; Domain of unknown function (DUF1744)
-
XM_047429018.1 → XP_047284974.1 DNA polymerase epsilon catalytic subunit A isoform X4
-
XM_011534799.3 → XP_011533101.1 DNA polymerase epsilon catalytic subunit A isoform X3
- Conserved Domains (4) summary
-
- cd05779
Location:268 → 471
- DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase
- cd05535
Location:531 → 1153
- POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...
- COG0417
Location:99 → 1165
- PolB; DNA polymerase elongation subunit (family B) [Replication, recombination and repair]
- pfam08490
Location:1529 → 1793
- DUF1744; Domain of unknown function (DUF1744)
RNA
-
XR_941395.3 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1 Alternate T2T-CHM13v2.0
- Range
-
132673921..132737569 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054372314.1 → XP_054228289.1 DNA polymerase epsilon catalytic subunit A isoform X5
-
XM_054372310.1 → XP_054228285.1 DNA polymerase epsilon catalytic subunit A isoform X1
- UniProtKB/TrEMBL
-
Q9Y5S4
-
XM_054372311.1 → XP_054228286.1 DNA polymerase epsilon catalytic subunit A isoform X2
- UniProtKB/TrEMBL
-
Q9UNF3
-
XM_054372313.1 → XP_054228288.1 DNA polymerase epsilon catalytic subunit A isoform X4
-
XM_054372312.1 → XP_054228287.1 DNA polymerase epsilon catalytic subunit A isoform X3
RNA
-
XR_008488621.1 RNA Sequence