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    neto-1 CUB domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186950, updated on 9-Dec-2024

    Summary

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    Official Symbol
    neto-1
    Official Full Name
    CUB domain-containing protein
    Primary source
    WormBase:WBGene00019360
    Locus tag
    CELE_K03E5.1
    See related
    AllianceGenome:WB:WBGene00019360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Orthologous to human NETO1 (neuropilin and tolloid like 1) and NETO2 (neuropilin and tolloid like 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See neto-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (3427148..3433207)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Cyclin-dependent kinase 2;Protein kinase domain-containing protein Neighboring gene ncRNA Neighboring gene CaLponIn-liKe proteins Neighboring gene Separin homolog sep-1 Neighboring gene non-specific serine/threonine protein kinase Neighboring gene Protein kinase domain-containing protein Neighboring gene DNA mismatch repair protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CUB domain-containing protein
    NP_491159.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3427148..3433207
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058758.5 → NP_491159.3  CUB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491159.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SMJ0, O61849
      Conserved Domains (2) summary
      cd00041
      Location:39 → 147
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:291 → 320
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    Nucleotide Protein
    Heading Accession and Version

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