F44A2.5 MIF4G domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F44A2.5
Official Full Name: MIF4G domain-containing protein
Primary source: WormBase:WBGene00018405
Locus tag: CELE_F44A2.5
See related: AllianceGenome:WB:WBGene00018405
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable translation activator activity. Predicted to be involved in regulation of translational initiation. Located in sarcoplasmic reticulum. Is expressed in pharynx. Orthologous to human MIF4GD (MIF4G domain containing). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F44A2.5 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 10

Sequence:: Chromosome: V; NC_003283.11 (9297632..9302496)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F44A2.5 (e-PCR)
- UniSTS:312328

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables translation activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in positive regulation of translation	IEA Inferred from Electronic Annotation more info
involved_in regulation of translational initiation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in sarcoplasmic reticulum	HDA more info	PubMed

General protein information

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Preferred Names: MIF4G domain-containing protein

NP_001367853.1

Confirmed by transcript evidence

NP_741589.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

9297632..9302496

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_171504.6 → NP_741589.2 MIF4G domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_741589.2

Status: REVIEWED

UniProtKB/TrEMBL

Q8MQ52

Conserved Domains (1) summary

smart00543
Location:173 → 372

MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
NM_001380723.3 → NP_001367853.1 MIF4G domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

H2L032