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    tasp-1 TASPase homolog [ Caenorhabditis elegans ]

    Gene ID: 176508, updated on 2-Nov-2024

    Summary

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    Official Symbol
    tasp-1
    Official Full Name
    TASPase homolog
    Primary source
    WormBase:WBGene00010480
    Locus tag
    CELE_K01G5.9
    See related
    AllianceGenome:WB:WBGene00010480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable threonine-type endopeptidase activity. Predicted to be involved in protein maturation. Predicted to be active in cytoplasm. Orthologous to human TASP1 (taspase 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tasp-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (10759385..10763006)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative E3 ubiquitin-protein ligase rnf113 Neighboring gene Haloacid dehalogenase-like hydrolase domain-containing protein 3 Neighboring gene Condensin complex subunit 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2. Wiesenfahrt T, et al. G3 (Bethesda), 2018 May 4. PMID 29593072, Free PMC Article
    2. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables threonine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    TASPase homolog
    NP_001379234.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class tasp

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10759385..10763006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392207.1 → NP_001379234.1  TASPase homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EF83
      Conserved Domains (1) summary
      cd04514
      Location:5 → 304
      Taspase1_like; Taspase 1 (threonine aspartase 1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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