Acbd5 acyl-CoA binding domain containing 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Acbd5provided by RGD
Official Full Name: acyl-CoA binding domain containing 5provided by RGD
Primary source: RGD:1309411
See related: EnsemblRapid:ENSRNOG00000017642 AllianceGenome:RGD:1309411
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process and pexophagy. Predicted to be located in nucleoplasm. Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in retinal dystrophy with leukodystrophy. Orthologous to human ACBD5 (acyl-CoA binding domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 205.2), Liver (RPKM 193.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17q12.3

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (90114250..90156286)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (85206178..85248909)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (89882465..89923982, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH131811 (e-PCR)
- UniSTS:215094

UniSTS:234876 (e-PCR)
- UniSTS:234876

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables fatty-acyl-CoA binding	IBA Inferred from Biological aspect of Ancestor more info
enables fatty-acyl-CoA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in pexophagy	IEA Inferred from Electronic Annotation more info
involved_in pexophagy	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in peroxisomal membrane	IEA Inferred from Electronic Annotation more info
is_active_in peroxisome	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisome	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: acyl-CoA-binding domain-containing protein 5

Names: acyl-Coenzyme A binding domain containing 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077635.3 → NP_001071103.1 acyl-CoA-binding domain-containing protein 5 isoform 1

See identical proteins and their annotated locations for NP_001071103.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000017

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:9 → 96

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
NM_001399254.1 → NP_001386183.1 acyl-CoA-binding domain-containing protein 5 isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000017

Related

ENSRNOP00000068154.2, ENSRNOT00000076964.3

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086035.1 Reference GRCr8

Range

90114250..90156286

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039095812.2 → XP_038951740.1 acyl-CoA-binding domain-containing protein 5 isoform X11

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:9 → 96

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_063276510.1 → XP_063132580.1 acyl-CoA-binding domain-containing protein 5 isoform X16
XM_039095813.2 → XP_038951741.1 acyl-CoA-binding domain-containing protein 5 isoform X14

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:9 → 96

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_063276511.1 → XP_063132581.1 acyl-CoA-binding domain-containing protein 5 isoform X17

UniProtKB/TrEMBL

A0A096MJJ6, A6KRZ4
XM_063276516.1 → XP_063132586.1 acyl-CoA-binding domain-containing protein 5 isoform X25
XM_063276519.1 → XP_063132589.1 acyl-CoA-binding domain-containing protein 5 isoform X28
XM_006254345.5 → XP_006254407.1 acyl-CoA-binding domain-containing protein 5 isoform X8

See identical proteins and their annotated locations for XP_006254407.1

UniProtKB/Swiss-Prot

A0FKI6, A0FKI7, Q3T1K2

UniProtKB/TrEMBL

B1H213

Related

ENSRNOP00000076762.2, ENSRNOT00000093822.2

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_006254343.3 → XP_006254405.1 acyl-CoA-binding domain-containing protein 5 isoform X5

UniProtKB/TrEMBL

A0A8I5Y939, B1H213

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_063276512.1 → XP_063132582.1 acyl-CoA-binding domain-containing protein 5 isoform X23
XM_017600582.3 → XP_017456071.1 acyl-CoA-binding domain-containing protein 5 isoform X20

UniProtKB/TrEMBL

B1H213
XM_006254351.5 → XP_006254413.1 acyl-CoA-binding domain-containing protein 5 isoform X4

UniProtKB/TrEMBL

A0A8I6AH07, B1H213

Related

ENSRNOP00000092017.1, ENSRNOT00000104691.2

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_017600577.3 → XP_017456066.1 acyl-CoA-binding domain-containing protein 5 isoform X2

UniProtKB/TrEMBL

B1H213
XM_063276507.1 → XP_063132577.1 acyl-CoA-binding domain-containing protein 5 isoform X12

Related

ENSRNOP00000107708.1, ENSRNOT00000130190.1
XM_063276508.1 → XP_063132578.1 acyl-CoA-binding domain-containing protein 5 isoform X13
XM_039095811.2 → XP_038951739.1 acyl-CoA-binding domain-containing protein 5 isoform X9

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_017600579.3 → XP_017456068.1 acyl-CoA-binding domain-containing protein 5 isoform X7

UniProtKB/TrEMBL

B1H213
XM_063276505.1 → XP_063132575.1 acyl-CoA-binding domain-containing protein 5 isoform X10
XM_017600575.3 → XP_017456064.1 acyl-CoA-binding domain-containing protein 5 isoform X1

UniProtKB/TrEMBL

B1H213
XM_063276517.1 → XP_063132587.1 acyl-CoA-binding domain-containing protein 5 isoform X26
XM_063276518.1 → XP_063132588.1 acyl-CoA-binding domain-containing protein 5 isoform X27
XM_017600581.3 → XP_017456070.1 acyl-CoA-binding domain-containing protein 5 isoform X18

UniProtKB/TrEMBL

B1H213
XM_039095815.2 → XP_038951743.1 acyl-CoA-binding domain-containing protein 5 isoform X19

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_039095817.2 → XP_038951745.1 acyl-CoA-binding domain-containing protein 5 isoform X22

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_039095816.2 → XP_038951744.1 acyl-CoA-binding domain-containing protein 5 isoform X21

UniProtKB/TrEMBL

B1H213

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_063276514.1 → XP_063132584.1 acyl-CoA-binding domain-containing protein 5 isoform X24
XM_063276504.1 → XP_063132574.1 acyl-CoA-binding domain-containing protein 5 isoform X6
XM_063276513.1 → XP_063132583.1 acyl-CoA-binding domain-containing protein 5 isoform X24
XM_039095810.2 → XP_038951738.1 acyl-CoA-binding domain-containing protein 5 isoform X3

UniProtKB/TrEMBL

A6KRZ3, B1H213

Conserved Domains (1) summary

cd00435
Location:45 → 132

ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
XM_063276509.1 → XP_063132579.1 acyl-CoA-binding domain-containing protein 5 isoform X15

Related

ENSRNOP00000112606.1, ENSRNOT00000138217.1