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    PML39 Pml39p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854864, updated on 4-Jan-2025

    Summary

    Official Symbol
    PML39
    Official Full Name
    Pml39p
    Primary source
    SGD:S000004575
    Locus tag
    YML107C
    See related
    AllianceGenome:SGD:S000004575; FungiDB:YML107C; VEuPathDB:YML107C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable zinc ion binding activity. Involved in maintenance of RNA location. Located in nuclear membrane. Part of nuclear pore nuclear basket. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See PML39 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (55265..56269, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Zds2p Neighboring gene uncharacterized protein Neighboring gene orotate phosphoribosyltransferase URA5 Neighboring gene RNA-binding signal recognition particle subunit SEC65

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables zinc ion binding  
    enables zinc ion binding PubMed 
    Component Evidence Code Pubs
    located_in membrane  
    located_in nuclear membrane PubMed 
    located_in nuclear membrane  
    part_of nuclear pore nuclear basket PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Pml39p
    NP_013600.2
    • Protein required for nuclear retention of unspliced pre-mRNAs; required along with Mlp1p and Pml1p; anchored to the nuclear pore complex through an interaction between its bimodular nuclear basket-interaction domain (NuBaID) and Mlp1p and Mlp2p; localizes to the nuclear basket enables linkage between subpopulations of Mlp1p; associates with the subset of nuclear pores farthest from the nucleolus; homologous to human ZC3HC1, a NuBaID containing protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      55265..56269 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182469.1 → NP_013600.2  TPA: Pml39p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013600.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0H7, Q03760
      UniProtKB/TrEMBL
      B3LLF2, G2WJU9
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