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    bsu1 vitatmin B6 import carrier Bsu1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361460, updated on 18-Sep-2024

    Summary

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    Official Symbol
    bsu1
    Official Full Name
    vitatmin B6 import carrier Bsu1
    Primary source
    PomBase:SPAC17A2.01
    Locus tag
    SPOM_SPAC17A2.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    car1; sod1; SPAC1B1.05
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    Genomic context

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    See bsu1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3550034..3552067)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TLC domain-containing protein Tlc4 Neighboring gene ncRNA Neighboring gene V-type ATPase V0 subunit d

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amiloride toxicity in the fission yeast Schizosaccharomyces pombe is released by thiamine and mutations in the thiamine-repressible gene car1. Niederberger C, et al. Gene, 1996 May 24. PMID 8675019
    2. Amiloride uptake and toxicity in fission yeast are caused by the pyridoxine transporter encoded by bsu1+ (car1+). Stolz J, et al. Eukaryot Cell, 2005 Feb. PMID 15701794, Free PMC Article
    3. Characterization of Thi9, a novel thiamine (Vitamin B1) transporter from Schizosaccharomyces pombe. Vogl C, et al. J Biol Chem, 2008 Mar 21. PMID 18201975
    4. Endocytosis is essential for dynamic translocation of a syntaxin 1 orthologue during fission yeast meiosis. Kashiwazaki J, et al. Mol Biol Cell, 2011 Oct. PMID 21832151, Free PMC Article
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Bsu1p (aka Car1p) represents a new high-affinity, plasma membrane-localized import carrier for pyridoxine, pyridoxal, and pyridoxamine. [bsu1]
      Title: Amiloride uptake and toxicity in fission yeast are caused by the pyridoxine transporter encoded by bsu1+ (car1+).
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables pyridoxal transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxamine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables thiamine transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in pyridoxal transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pyridoxamine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pyridoxine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in thiamine transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in fungal-type vacuole IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vitatmin B6 import carrier Bsu1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3550034..3552067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356120.2 → NP_001342836.1  vitatmin B6 import carrier Bsu1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13866, P33532
      Conserved Domains (2) summary
      TIGR00880
      Location:124 → 260
      2_A_01_02; Multidrug resistance protein
      pfam07690
      Location:82 → 466
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

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