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    CFF1 Cff1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854896, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CFF1
    Official Full Name
    Cff1p
    Primary source
    SGD:S000004544
    Locus tag
    YML079W
    See related
    AllianceGenome:SGD:S000004544; FungiDB:YML079W; VEuPathDB:YML079W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Acts upstream of or within pyrimidine-containing compound metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See CFF1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (110247..110852)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Tda9p Neighboring gene tRNA dihydrouridine synthase Neighboring gene peptidylprolyl isomerase CPR3 Neighboring gene TRAPP subunit BET5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamic metabolome profiling uncovers potential TOR signaling genes. Reichling S, et al. Elife, 2023 Jan 4. PMID 36598488, Free PMC Article
    2. Saccharomyces cerevisiae Requires CFF1 To Produce 4-Hydroxy-5-Methylfuran-3(2H)-One, a Mimic of the Bacterial Quorum-Sensing Autoinducer AI-2. Valastyan JS, et al. mBio, 2021 Mar 9. PMID 33688008, Free PMC Article
    3. Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold. Zhou CZ, et al. Protein Sci, 2005 Jan. PMID 15608122, Free PMC Article
    4. A Protein-Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20. Joshua IM, et al. Int J Mol Sci, 2023 Nov 2. PMID 37958899, Free PMC Article
    5. Selective defects in gene expression control genome instability in yeast splicing mutants. Tam AS, et al. Mol Biol Cell, 2019 Jan 15. PMID 30462576, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pyrimidine-containing compound metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Cff1p
    NP_013632.1
    • Protein required for production of 4-hydroxy-5-methylfuran-3(2H)-one (MHF); cupin superfamily protein; has structural resemblance to plant storage and ligand binding proteins (canavalin, glycinin, auxin binding protein) and to some enzymes (epimerase, germin); localizes to nucleus and cytoplasm

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      110247..110852
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182438.1 → NP_013632.1  TPA: Cff1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013632.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0K4, Q03629
      UniProtKB/TrEMBL
      A6ZLY6, B3LLH7, B5VP50, C7GW14, C8ZEC6, G2WJX6, N1P0T8
      Conserved Domains (1) summary
      COG3542
      Location:23 → 201
      CFF1; Predicted sugar epimerase, cupin superfamily [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03629.1

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