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    rpn6 proteasome regulatory subunit Rpn6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541807, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rpn6
    Official Full Name
    proteasome regulatory subunit Rpn6
    Primary source
    PomBase:SPAC23G3.11
    Locus tag
    SPOM_SPAC23G3.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rpn6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (887648..889096)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ubiquitin hydrolase Ubp7 Neighboring gene ncRNA Neighboring gene transcription factor TFIID complex subunit Taf4 Neighboring gene SWI/SNF and RSC complex subunit Ssr3 Neighboring gene serine protease Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together. Pathare GR, et al. Proc Natl Acad Sci U S A, 2012 Jan 3. PMID 22187461, Free PMC Article
    2. Schizosaccharomyces pombe Dss1p is a DNA damage checkpoint protein that recruits Rad24p, Cdc25p, and Rae1p to DNA double-strand breaks. Selvanathan SP, et al. J Biol Chem, 2010 May 7. PMID 20231270, Free PMC Article
    3. The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein. Taricani L, et al. J Biol Chem, 2002 Mar 22. PMID 11751918
    4. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Lasker K, et al. Proc Natl Acad Sci U S A, 2012 Jan 31. PMID 22307589, Free PMC Article
    5. Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Bohn S, et al. Proc Natl Acad Sci U S A, 2010 Dec 7. PMID 21098295, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables structural molecule activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IC
    Inferred by Curator
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proteasome regulatory particle, lid subcomplex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proteasome regulatory subunit Rpn6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      887648..889096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018508.3 → NP_593111.1  proteasome regulatory subunit Rpn6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593111.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7S2
      Conserved Domains (2) summary
      COG5159
      Location:1 → 421
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:283 → 387
      PCI; PCI domain
    Nucleotide Protein
    Heading Accession and Version

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