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    Scamp2 secretory carrier membrane protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 24044, updated on 9-Dec-2024

    Summary

    Official Symbol
    Scamp2provided by MGI
    Official Full Name
    secretory carrier membrane protein 2provided by MGI
    Primary source
    MGI:MGI:1346518
    See related
    Ensembl:ENSMUSG00000040188 AllianceGenome:MGI:1346518
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sc2
    Summary
    Predicted to be involved in protein transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in recycling endosome membrane and trans-Golgi network membrane. Orthologous to human SCAMP2 (secretory carrier membrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 92.7), testis adult (RPKM 90.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Scamp2 in Genome Data Viewer
    Location:
    9 B; 9 31.05 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57468227..57496081)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57560944..57588798)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11408 Neighboring gene cytochrome c oxidase subunit 5A Neighboring gene family with sequence similarity 219, member B Neighboring gene mannose phosphate isomerase Neighboring gene STARR-positive B cell enhancer ABC_E3834 Neighboring gene STARR-positive B cell enhancer ABC_E3835 Neighboring gene unc-51-like kinase 3 Neighboring gene complexin 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in recycling endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in trans-Golgi network membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in trans-Golgi network membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    secretory carrier-associated membrane protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378928.1NP_001365857.1  secretory carrier-associated membrane protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC122528, AC164548
      UniProtKB/TrEMBL
      Q3TU28
      Conserved Domains (1) summary
      pfam04144
      Location:161336
      SCAMP; SCAMP family
    2. NM_022813.3NP_073724.1  secretory carrier-associated membrane protein 2 isoform 2

      See identical proteins and their annotated locations for NP_073724.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AF295402, AK161002, CA979044, CX217627
      Consensus CDS
      CCDS23224.1
      UniProtKB/Swiss-Prot
      Q9ERN0
      UniProtKB/TrEMBL
      Q3TAL2, Q3TU28
      Related
      ENSMUSP00000038350.10, ENSMUST00000045791.11
      Conserved Domains (1) summary
      pfam04144
      Location:118293
      SCAMP; SCAMP family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      57468227..57496081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)