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Envelope surface glycoprotein gp120
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env
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Tandem affinity purification and mass spectrometry analysis identify adenosine deaminase RNA-specific binding protein (ADAR), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
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env
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ADAR1 inhibits HIV-1 viral protein synthesis such as p24 CA, gp120, and p65 Pol proteins in the various cell lines. The catalytic motif of ADAR1 deaminase domain is required for the inhibition function |
PubMed
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env
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Overexpression of ADAR1 increases the levels of gp120, p24, and Nef in HIV-1 producer cells, which requires inhibition of the RNA-activated protein kinase PKR |
PubMed
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env
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HIV-1 gp120 inhibits adenosine deaminase (ADA) binding to CD26 (dipeptidyl-peptidase 4) in both CD4+ and CD4- cells; this effect requires the interaction of gp120 with CD4 or CXCR4 |
PubMed
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Gag-Pol
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gag-pol
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Tandem affinity purification and mass spectrometry analysis identify adenosine deaminase RNA-specific binding protein (ADAR), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
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Nef
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nef
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Tandem affinity purification and mass spectrometry analysis identify adenosine deaminase RNA-specific binding protein (ADAR), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
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nef
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Overexpression of ADAR1 increases the levels of gp120, p24, and Nef in HIV-1 producer cells, which requires inhibition of the RNA-activated protein kinase PKR |
PubMed
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Pr55(Gag)
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gag
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p55 Gag associates with ADAR1 |
PubMed
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gag
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Tandem affinity purification and mass spectrometry analysis identify adenosine deaminase RNA-specific binding protein (ADAR), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
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Rev
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rev
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HIV-1 Rev interacting protein, adenosine deaminase, RNA-specific (ADAR), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with ADAR is increased by RRE |
PubMed
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rev
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ADAR1-mediated A-to-G mutations in RRE region of the env gene affect the binding of HIV-1 Rev |
PubMed
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Tat
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tat
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Expression of HIV-1 Tat downregulates the abundance of RNA-specific adenosine deaminase (ADAR) in the nucleoli of Jurkat T-cells |
PubMed
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capsid
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gag
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ADAR1 inhibits HIV-1 viral protein synthesis such as p24 CA, gp120, and p65 Pol proteins in the various cell lines. The catalytic motif of ADAR1 deaminase domain is required for the inhibition function |
PubMed
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gag
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Overexpression of ADAR1 increases the levels of gp120, p24, and Nef in HIV-1 producer cells, which requires inhibition of the RNA-activated protein kinase PKR |
PubMed
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reverse transcriptase
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gag-pol
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ADAR1 inhibits HIV-1 viral protein synthesis such as p24 CA, gp120, and p65 Pol proteins in the various cell lines. The catalytic motif of ADAR1 deaminase domain is required for the inhibition function |
PubMed
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