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    KLF4 Kruppel like factor 4 [ Gallus gallus (chicken) ]

    Gene ID: 770254, updated on 17-Aug-2024

    Summary

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    Symbol
    KLF4provided by CGNC
    Full Name
    Kruppel like factor 4provided by CGNC
    Primary source
    CGNC:28582
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See KLF4 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (56393942..56398448, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (56393942..56398448, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 462 Neighboring gene microRNA 6565 Neighboring gene RAD23 homolog B, nucleotide excision repair protein Neighboring gene uncharacterized LOC121108643 Neighboring gene uncharacterized LOC121108534 Neighboring gene uncharacterized LOC107052355

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. miR-7 regulates the apoptosis of chicken primary myoblasts through the KLF4 gene. Zhang X, et al. Br Poult Sci, 2022 Feb. PMID 34287083
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. miR-7 regulates the apoptosis of chicken primary myoblasts through the KLF4 gene.
      Title: miR-7 regulates the apoptosis of chicken primary myoblasts through the KLF4 gene.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Krueppel-like factor 4
    Names
    Kruppel-like factor 4 (gut)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      56393942..56398448 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004949369.5 → XP_004949426.2  Krueppel-like factor 4 isoform X1

      Conserved Domains (3) summary
      smart00355
      Location:435 → 457
      ZnF_C2H2; zinc finger
      COG5048
      Location:382 → 437
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:377 → 399
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_046905543.1 → XP_046761499.1  Krueppel-like factor 4 isoform X2

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      56393942..56398448 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936072.1 → XP_046792028.1  Krueppel-like factor 4 isoform X1

    2. XM_046936073.1 → XP_046792029.1  Krueppel-like factor 4 isoform X2

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials