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    LAMB4 laminin subunit beta 4 [ Gallus gallus (chicken) ]

    Gene ID: 396076, updated on 3-Dec-2024

    Summary

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    Symbol
    LAMB4provided by CGNC
    Full Name
    laminin subunit beta 4provided by CGNC
    Primary source
    CGNC:5987
    See related
    Ensembl:ENSGALG00010010829
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human all
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    Genomic context

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    See LAMB4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (15111982..15165811, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (15247241..15303379, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108798 Neighboring gene dihydrolipoamide dehydrogenase Neighboring gene laminin subunit beta 1 Neighboring gene uncharacterized LOC112533030 Neighboring gene ERGIC and golgi 2 Neighboring gene leucine rich repeat kinase 2 Neighboring gene uncharacterized LOC121108850 Neighboring gene solute carrier family 2 member 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulated expression of a novel laminin beta subunit during the development of the chick embryo. Ybot-Gonzalez P, et al. Differentiation, 1995 Nov. PMID 8575643
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in basement membrane assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of laminin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit beta-4
    Names
    laminin beta x subunit
    laminin, beta 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199313.2 → NP_001186242.2  laminin subunit beta-4

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0Y6P1, A0A8V0YAI8
      Related
      ENSGALP00010014622.1, ENSGALT00010025960.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      15111982..15165811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040659207.2 → XP_040515141.1  laminin subunit beta-4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y6P1
      Conserved Domains (6) summary
      smart00180
      Location:1129 → 1174
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      COG1196
      Location:1232 → 1775
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:865 → 907
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00185
      Location:943 → 987
      TNFRSF; CRD2 [structural motif]
      cl02806
      Location:26 → 266
      Laminin_N; Laminin N-terminal (Domain VI)
      cl22855
      Location:921 → 1006
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    2. XM_040659127.2 → XP_040515061.1  laminin subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y6P1
      Conserved Domains (6) summary
      smart00180
      Location:1129 → 1174
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      COG1196
      Location:1232 → 1801
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:865 → 907
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00185
      Location:943 → 987
      TNFRSF; CRD2 [structural motif]
      cl02806
      Location:26 → 266
      Laminin_N; Laminin N-terminal (Domain VI)
      cl22855
      Location:921 → 1006
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    3. XM_040659047.2 → XP_040514981.1  laminin subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y6P1
      Conserved Domains (6) summary
      smart00180
      Location:1129 → 1174
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      COG1196
      Location:1232 → 1801
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:865 → 907
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00185
      Location:943 → 987
      TNFRSF; CRD2 [structural motif]
      cl02806
      Location:26 → 266
      Laminin_N; Laminin N-terminal (Domain VI)
      cl22855
      Location:921 → 1006
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    4. XM_040659283.2 → XP_040515217.1  laminin subunit beta-4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y6P1
      Conserved Domains (6) summary
      smart00180
      Location:986 → 1031
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      COG1196
      Location:1089 → 1658
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:722 → 764
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00185
      Location:800 → 844
      TNFRSF; CRD2 [structural motif]
      cl02806
      Location:1 → 123
      Laminin_N; Laminin N-terminal (Domain VI)
      cl22855
      Location:778 → 863
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    5. XM_040659351.2 → XP_040515285.1  laminin subunit beta-4 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y6P1
      Conserved Domains (6) summary
      smart00180
      Location:904 → 949
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      COG1196
      Location:1007 → 1573
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:640 → 682
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00185
      Location:718 → 762
      TNFRSF; CRD2 [structural motif]
      cl02806
      Location:1 → 41
      Laminin_N; Laminin N-terminal (Domain VI)
      cl22855
      Location:696 → 781
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      15247241..15303379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046906781.1 → XP_046762737.1  laminin subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y6P1

    2. XM_046906782.1 → XP_046762738.1  laminin subunit beta-4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y6P1

    3. XM_046906780.1 → XP_046762736.1  laminin subunit beta-4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y6P1
    Nucleotide Protein
    Heading Accession and Version

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