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    TSKU tsukushi, small leucine rich proteoglycan [ Bos taurus (domestic cattle) ]

    Gene ID: 529661, updated on 30-Jan-2025

    Summary

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    Official Symbol
    TSKUprovided by VGNC
    Official Full Name
    tsukushi, small leucine rich proteoglycanprovided by VGNC
    Primary source
    VGNC:VGNC:54896
    See related
    EnsemblRapid:ENSBTAG00070028744
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TSKU in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (56179611..56193003)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112441534 Neighboring gene guanylate cyclase 2E Neighboring gene basic proline-rich protein-like Neighboring gene alkaline ceramidase 3 Neighboring gene heterogeneous nuclear ribonucleoprotein K-like Neighboring gene bcl-2-like protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC165974

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tsukushi
    Names
    tsukushi small leucine rich proteoglycan homolog
    tsukushin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103268.2 → NP_001096738.2  tsukushi precursor

      Status: VALIDATED

      Source sequence(s)
      NKLS02000015
      UniProtKB/TrEMBL
      A0AAA9S4M0
      Related
      ENSBTAP00070039427.1, ENSBTAT00070065328.1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56179611..56193003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059874762.1 → XP_059730745.1  tsukushi isoform X1

      UniProtKB/TrEMBL
      A0AAA9S008, A0AAA9S4M0
      Related
      ENSBTAP00070039441.1, ENSBTAT00070065344.1

    2. XM_010812724.4 → XP_010811026.1  tsukushi isoform X1

      See identical proteins and their annotated locations for XP_010811026.1

      UniProtKB/TrEMBL
      A0AAA9S008, A0AAA9S4M0
      Conserved Domains (3) summary
      cd00116
      Location:43 → 296
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:91 → 114
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:68 → 125
      LRR_8; Leucine rich repeat

    3. XM_010812723.4 → XP_010811025.1  tsukushi isoform X1

      See identical proteins and their annotated locations for XP_010811025.1

      UniProtKB/TrEMBL
      A0AAA9S008, A0AAA9S4M0
      Related
      ENSBTAP00070039450.1, ENSBTAT00070065355.1
      Conserved Domains (3) summary
      cd00116
      Location:43 → 296
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:91 → 114
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:68 → 125
      LRR_8; Leucine rich repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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