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    MTF1 metal regulatory transcription factor 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509960, updated on 1-Jan-2025

    Summary

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    Official Symbol
    MTF1provided by VGNC
    Official Full Name
    metal regulatory transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:31722
    See related
    BGD:BT14590; Ensembl:ENSBTAG00000006511
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MTF1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (108063028..108107586)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3a subunit 3 Neighboring gene inositol polyphosphate-5-phosphatase B Neighboring gene chromosome 3 C1orf122 homolog Neighboring gene yrdC N6-threonylcarbamoyltransferase domain containing Neighboring gene mannosidase endo-alpha like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC142744

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metal regulatory transcription factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035080.2 → NP_001030252.2  metal regulatory transcription factor 1

      Status: PROVISIONAL

      Source sequence(s)
      BC123774
      UniProtKB/TrEMBL
      F1MHE3, Q08DF6, Q5E9H4
      Related
      ENSBTAP00000008535.5, ENSBTAT00000008535.7
      Conserved Domains (4) summary
      COG5048
      Location:93 → 291
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:234 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04499
      Location:322 → 416
      SAPS; SIT4 phosphatase-associated protein
      pfam13465
      Location:245 → 271
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      108063028..108107586
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059883250.1 → XP_059739233.1  metal regulatory transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      F1MHE3, Q08DF6, Q5E9H4

    2. XM_005204693.5 → XP_005204750.1  metal regulatory transcription factor 1 isoform X2

      UniProtKB/TrEMBL
      Q5E9H4
      Conserved Domains (4) summary
      COG5048
      Location:93 → 291
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:234 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04499
      Location:322 → 416
      SAPS; SIT4 phosphatase-associated protein
      pfam13465
      Location:245 → 271
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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