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    CENPF centromere protein F [ Bos taurus (domestic cattle) ]

    Gene ID: 533089, updated on 27-Dec-2024

    Summary

    Official Symbol
    CENPFprovided by VGNC
    Official Full Name
    centromere protein Fprovided by VGNC
    Primary source
    VGNC:VGNC:27176
    See related
    BGD:BT14954; Ensembl:ENSBTAG00000024449
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See CENPF in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (68929293..68991898, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342496 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene uncharacterized LOC112441860 Neighboring gene protein tyrosine phosphatase non-receptor type 14 Neighboring gene SET and MYND domain containing 2

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables dynein complex binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in metaphase chromosome alignment IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of G2/M transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    centromere protein F
    Names
    mitosin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256586.1NP_001243515.1  centromere protein F

      Status: VALIDATED

      Source sequence(s)
      AAFC03017426, AAFC03031658, AAFC03031660
      UniProtKB/TrEMBL
      A0AAA9SYD6
      Conserved Domains (8) summary
      COG1196
      Location:4071163
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG1340
      Location:25432817
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      COG1579
      Location:24222564
      COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
      pfam07851
      Location:19612102
      TMPIT; TMPIT-like protein
      pfam10473
      Location:22762414
      CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
      pfam10481
      Location:1307
      CENP-F_N; Cenp-F N-terminal domain
      pfam10490
      Location:29322978
      CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
      pfam16046
      Location:21682238
      FAM76; FAM76 protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      68929293..68991898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005217369.5XP_005217426.1  centromere protein F isoform X1

      UniProtKB/TrEMBL
      A0AAA9SYD6, F1N1F8
      Related
      ENSBTAP00000033816.5, ENSBTAT00000033913.6
      Conserved Domains (7) summary
      COG1196
      Location:4071163
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      COG1340
      Location:27232997
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam07851
      Location:19612102
      TMPIT; TMPIT-like protein
      pfam10473
      Location:22762415
      CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
      pfam10481
      Location:1307
      CENP-F_N; Cenp-F N-terminal domain
      pfam10490
      Location:31123158
      CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
      pfam16046
      Location:21682238
      FAM76; FAM76 protein