Replication interactions
Interaction |
Pubs |
Knockdown of SPTBN1 by siRNA inhibits HIV-1 replication in primary macrophages |
PubMed
|
Knockdown of spectrin, beta, non-erythrocytic 1 (SPTBN1) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Pr55(Gag)
|
gag
|
HIV-1 Gag co-localizes with SPTBN1 both at the plasma membrane and in cytoplasm |
PubMed
|
Rev
|
rev
|
HIV-1 Rev interacting protein, spectrin, beta, non-erythrocytic 1 (SPTBN1), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells |
PubMed
|
Tat
|
tat
|
Spectrin, beta, non-erythrocytic 1 (SPTBN1) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS |
PubMed
|
Vpr
|
vpr
|
Co-localization of Vpr-GFP-labeled virion and SPTBN1 is observed on plasma membrane (PM) and the intracellular side of PM |
PubMed
|
capsid
|
gag
|
HIV-1 CA associates with SPTBN1 in cells |
PubMed
|
matrix
|
gag
|
HIV-1 MA associates with SPTBN1 in cells |
PubMed
|
retropepsin
|
gag-pol
|
A number of focal adhesion plaque proteins are specifically cleaved by HIV-1 protease, including fimbrin, focal adhesion plaque kinase (FAK), talin, and, to a lesser extent, filamin, spectrin and fibronectin |
PubMed
|
Go to the HIV-1, Human Interaction Database