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    RTC6 putative mitochondrial 54S ribosomal protein RTC6 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855918, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RTC6
    Official Full Name
    putative mitochondrial 54S ribosomal protein RTC6
    Primary source
    SGD:S000007224
    Locus tag
    YPL183W-A
    See related
    AllianceGenome:SGD:S000007224; FungiDB:YPL183W-A; VEuPathDB:YPL183W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    bL36m; TAE4
    Summary
    Enables zinc ion binding activity. Involved in ribosome biogenesis. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL36 (mitochondrial ribosomal protein L36). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RTC6 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (199095..199376)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Uip4p Neighboring gene Mrn1p Neighboring gene Rtt10p Neighboring gene Cti6p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The zinc finger motif in the mitochondrial large ribosomal subunit protein bL36m is essential for optimal yeast mitoribosome assembly and function. Zhong H, et al. Biochim Biophys Acta Mol Cell Res, 2024 Apr. PMID 38493895,
    2. Characterization of new proteins found by analysis of short open reading frames from the full yeast genome. Andrade MA, et al. Yeast, 1997 Nov. PMID 9392081
    3. Identification of gold nanoparticle-resistant mutants of Saccharomyces cerevisiae suggests a role for respiratory metabolism in mediating toxicity. Smith MR, et al. Appl Environ Microbiol, 2013 Jan. PMID 23144132, Free PMC Article
    4. The SUN protein Mps3 is required for spindle pole body insertion into the nuclear membrane and nuclear envelope homeostasis. Friederichs JM, et al. PLoS Genet, 2011 Nov. PMID 22125491, Free PMC Article
    5. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in ribosome biogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosome biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative mitochondrial 54S ribosomal protein RTC6
    NP_015141.1
    • Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      199095..199376
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184317.1 → NP_015141.1  TPA: putative mitochondrial 54S ribosomal protein RTC6 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015141.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3I5, O14464
      UniProtKB/TrEMBL
      A6ZW70, B3LKP5, C7GJD2, C8ZIJ4, N1NWP2
      Conserved Domains (1) summary
      pfam00444
      Location:56 → 93
      Ribosomal_L36; Ribosomal protein L36
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O14464.1

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