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    ATG19 Atg19p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854072, updated on 9-Dec-2024

    Summary

    Official Symbol
    ATG19
    Official Full Name
    Atg19p
    Primary source
    SGD:S000005442
    Locus tag
    YOL082W
    See related
    AllianceGenome:SGD:S000005442; FungiDB:YOL082W; VEuPathDB:YOL082W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CVT19
    Summary
    Enables protein-macromolecule adaptor activity. Involved in ERAD pathway; protein-containing complex localization; and vesicle organization. Located in phagophore assembly site. Part of Cvt complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ATG19 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (168727..169974)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Phm7p Neighboring gene Atg34p Neighboring gene Ras GTPase activating protein IRA2 Neighboring gene putative 3'-5' exonuclease

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in ERAD pathway PubMed 
    involved_in autophagy  
    involved_in protein transport  
    involved_in protein-containing complex localization PubMed 
    involved_in protein-containing complex localization PubMed 
    involved_in vesicle organization PubMed 
    Component Evidence Code Pubs
    part_of Cvt complex PubMed 
    located_in cytoplasm PubMed 
    located_in cytosol PubMed 
    located_in membrane  
    located_in phagophore assembly site PubMed 
    located_in phagophore assembly site membrane  

    General protein information

    Preferred Names
    Atg19p
    NP_014559.1
    • Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway; delivers cargo proteins aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p) to the phagophore assembly site for packaging into Cvt vesicles; interaction with Atg19p during the Cvt pathway requires phosphorylation by Hrr25p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      168727..169974
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183336.1 → NP_014559.1  TPA: Atg19p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014559.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZNC8, D6W1Y6, P35193, Q6B1A6
      UniProtKB/TrEMBL
      B3LIY1, B5VRH2, C7GK46, C8ZHN6, G2WMF3, N1NX67
      Conserved Domains (1) summary
      cd12213
      Location:259 → 362
      ABD; Alpha-Mannosidase Binding Domain of Atg19/34
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