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    Fbll1 fibrillarin-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 237730, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fbll1provided by MGI
    Official Full Name
    fibrillarin-like 1provided by MGI
    Primary source
    MGI:MGI:3034689
    See related
    Ensembl:ENSMUSG00000051062 AllianceGenome:MGI:3034689
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable RNA binding activity; histone H2AQ104 methyltransferase activity; and rRNA methyltransferase activity. Acts upstream of or within blastocyst hatching. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Predicted to be active in Cajal body and nucleolus. Is expressed in early conceptus. Orthologous to human FBLL1 (fibrillarin like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Fbll1 in Genome Data Viewer
    Location:
    11 A4; 11 21.96 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (35688207..35689711, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (35797380..35798884, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene slit guidance ligand 3 Neighboring gene predicted gene, 46278 Neighboring gene STARR-positive B cell enhancer ABC_E1137 Neighboring gene microRNA 103-1 Neighboring gene STARR-positive B cell enhancer ABC_E9361 Neighboring gene STARR-positive B cell enhancer ABC_E6965 Neighboring gene pantothenate kinase 3 Neighboring gene arginyl-tRNA synthetase 1 Neighboring gene WW, C2 and coiled-coil domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_29194

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Clone Names

    • MGC62475

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding  
    enables RNA binding  
    enables histone H2AQ104 methyltransferase activity  
    enables methyltransferase activity  
    enables rRNA methyltransferase activity  
    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching PubMed 
    involved_in box C/D sno(s)RNA 3'-end processing  
    involved_in methylation  
    involved_in rRNA methylation  
    involved_in rRNA processing  
    Component Evidence Code Pubs
    is_active_in Cajal body  
    part_of box C/D methylation guide snoRNP complex  
    located_in fibrillar center  
    located_in fibrillar center  
    is_active_in nucleolus  
    located_in nucleoplasm  
    located_in nucleoplasm  
    part_of ribonucleoprotein complex  
    part_of small-subunit processome  

    General protein information

    Preferred Names
    rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1
    Names
    protein-glutamine methyltransferase
    NP_001004147.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004147.3NP_001004147.1  rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1

      See identical proteins and their annotated locations for NP_001004147.1

      Status: VALIDATED

      Source sequence(s)
      BC052068, BE648485, BU701095
      Consensus CDS
      CCDS36128.1
      UniProtKB/Swiss-Prot
      Q80WS3
      Related
      ENSMUSP00000128889.2, ENSMUST00000160726.4
      Conserved Domains (1) summary
      PTZ00146
      Location:73314
      PTZ00146; fibrillarin; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      35688207..35689711 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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