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    Lrrc3c leucine rich repeat containing 3C [ Mus musculus (house mouse) ]

    Gene ID: 192852, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrrc3cprovided by MGI
    Official Full Name
    leucine rich repeat containing 3Cprovided by MGI
    Primary source
    MGI:MGI:2684858
    See related
    Ensembl:ENSMUSG00000086545 AllianceGenome:MGI:2684858
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm12
    Summary
    Predicted to be active in extracellular matrix and extracellular space. Orthologous to human LRRC3C (leucine rich repeat containing 3C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc3c in Genome Data Viewer
    Location:
    11 D; 11 62.12 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (98489117..98490412)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (98598291..98599586)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31460 Neighboring gene ORM1-like 3 (S. cerevisiae) Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:98448640-98448823 Neighboring gene STARR-seq mESC enhancer starr_30672 Neighboring gene serine and arginine rich splicing factor 3, pseudogene Neighboring gene gasdermin A3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 3C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195544.1 → NP_001182473.1  leucine-rich repeat-containing protein 3C precursor

      Status: PROVISIONAL

      Source sequence(s)
      AL591125
      Consensus CDS
      CCDS83891.1
      UniProtKB/TrEMBL
      A0A1B0GRI5
      Related
      ENSMUSP00000147537.2, ENSMUST00000142268.3
      Conserved Domains (3) summary
      sd00031
      Location:40 → 59
      LRR_1; leucine-rich repeat [structural motif]
      pfam12799
      Location:61 → 99
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:61 → 119
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      98489117..98490412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_020432.1: Suppressed sequence

      Description
      NG_020432.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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