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    Coro7 coronin 7 [ Mus musculus (house mouse) ]

    Gene ID: 78885, updated on 9-Dec-2024

    Summary

    Official Symbol
    Coro7provided by MGI
    Official Full Name
    coronin 7provided by MGI
    Primary source
    MGI:MGI:1926135
    See related
    Ensembl:ENSMUSG00000039637 AllianceGenome:MGI:1926135
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610011B16Rik
    Summary
    Predicted to enable actin binding activity. Acts upstream of or within several processes, including Golgi organization; actin filament organization; and establishment of cell polarity. Located in Golgi apparatus and membrane. Is expressed in hemolymphoid system; nervous system; neural retina; and small intestine. Orthologous to several human genes including CORO7 (coronin 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 73.3), spleen adult (RPKM 53.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Coro7 in Genome Data Viewer
    Location:
    16 A1; 16 2.45 cM
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (4444748..4497584, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (4626884..4679720, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA D330022H12 gene Neighboring gene GLIS family zinc finger 2 Neighboring gene presequence translocase-asssociated motor 16 Neighboring gene STARR-seq mESC enhancer starr_39940 Neighboring gene vasorin Neighboring gene STARR-positive B cell enhancer ABC_E10885 Neighboring gene STARR-seq mESC enhancer starr_39941 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:4683706-4683859 Neighboring gene DnaJ heat shock protein family (Hsp40) member A3 Neighboring gene STARR-seq mESC enhancer starr_39942 Neighboring gene NmrA-like family domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within Golgi organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in Golgi to endosome transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in actin filament polymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within establishment of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of hippo signaling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    coronin-7
    Names
    70 kDa WD repeat tumor rejection antigen homolog
    crn7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030205.4NP_084481.3  coronin-7

      See identical proteins and their annotated locations for NP_084481.3

      Status: PROVISIONAL

      Source sequence(s)
      BC061006
      Consensus CDS
      CCDS37242.1
      UniProtKB/Swiss-Prot
      Q3UDJ4, Q6P8Y8, Q8C9V7, Q9D2V7
      Related
      ENSMUSP00000048489.7, ENSMUST00000038552.13
      Conserved Domains (4) summary
      pfam08953
      Location:467524
      DUF1899; Domain of unknown function (DUF1899)
      pfam16300
      Location:805849
      WD40_4; Type of WD40 repeat
      sd00039
      Location:545589
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:543665
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      4444748..4497584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)