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    C23G10.7 putative tRNA (uracil-O(2)-)-methyltransferase [ Caenorhabditis elegans ]

    Gene ID: 175876, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C23G10.7
    Official Full Name
    putative tRNA (uracil-O(2)-)-methyltransferase
    Primary source
    WormBase:WBGene00016014
    Locus tag
    CELE_C23G10.7
    See related
    AllianceGenome:WB:WBGene00016014
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable tRNA (uridine) methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in cytoplasm. Orthologous to human TRMT44 (tRNA methyltransferase 44 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C23G10.7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    10
    Sequence:
    Chromosome: III; NC_003281.10 (6195981..6198414, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene UDP-glucuronosyltransferase Neighboring gene ncRNA Neighboring gene 26S proteasome non-ATPase regulatory subunit 1 Neighboring gene NADAR domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (uridine) methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative tRNA (uracil-O(2)-)-methyltransferase
    NP_001033350.1
    • Confirmed by transcript evidence
    NP_741176.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6195981..6198414 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171872.6 → NP_741176.2  putative tRNA (uracil-O(2)-)-methyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741176.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q45EK7
      Conserved Domains (1) summary
      pfam07757
      Location:186 → 294
      AdoMet_MTase; Predicted AdoMet-dependent methyltransferase

    2. NM_001038261.5 → NP_001033350.1  putative tRNA (uracil-O(2)-)-methyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033350.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q45EK5, Q45EK6, Q45EK7
      Conserved Domains (1) summary
      pfam07757
      Location:186 → 294
      AdoMet_MTase; Predicted AdoMet-dependent methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q45EK7.1

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