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    lig NAD-dependent DNA ligase LigA [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879269, updated on 11-Sep-2024

    Summary

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    Gene symbol
    lig
    Gene description
    NAD-dependent DNA ligase LigA
    Locus tag
    PA1529
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1666025..1668409)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene cell division protein ZipA Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene 4.5S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of a temperature-sensitive DNA ligase from Escherichia coli. Lavesa-Curto M, et al. Microbiology (Reading), 2004 Dec. PMID 15583169
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables DNA ligase (NAD+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NAD-dependent DNA ligase LigA
    NP_250220.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1666025..1668409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250220.1 NAD-dependent DNA ligase LigA [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250220.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9I3I4
      Conserved Domains (2) summary
      PRK07956
      Location:3 → 790
      ligA; NAD-dependent DNA ligase LigA; Validated
      cl22429
      Location:628 → 686
      HHH_5; Helix-hairpin-helix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I3I4.1

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